To: Mark Bong who wrote (1965 ) 11/7/2000 7:42:36 AM From: scott_jiminez Respond to of 52153 Mark - the following is the result of (your insightful questions and) a conversation with IR at HDII: HDII and CDIC are not competing for the same market. The device that won FDA approval for HDII on Friday assesses arterial elasticity (as a gauge of cardiovascular integrity). This is accomplished through waveform analysis of cardiac output following a 30 sec. measurement in a doctors office. Assessment is the key word here. CDIC's device is incorporated into a series of machines which monitors a patient's cardiovascular status over time. Some of CDIC's measurements overlap with those of the HDII readings; however, the two devices were designed, and are used, for very different purposes. HDII's profilor is intended for an in-office assessment of CV integrity; CDIC's device is intended as a component of chronic monitoring of CV status. Neither can produce the data of the other. Other issues... HDII is a very small company at present. There's little debate that the FDA approval is about to change that dramatically. The company is very conservative about this transition phase and is proceeding with extreme caution so as not to jump forward (for example, immediately quadrupling its sales force) too fast. They are completely aware of the reimbursement maze and, with the approval now behind them, this is priority one. They have spoken with the AMA regarding the 'reimbursability' of the profilor; while there is nothing else like it extant, they were told that some of the existing CPT codes approximate the use of the profilor so that a transition to reimbursement for HDII will likely not have to be initiated from ground zero. Certainly no guarantees; HDII is focusing most of their current energies on establishing the contacts and environment necessary for payers to support the profilor. The central message was that they plan to do proceed with methodical caution so as not to be caught in the trap of rapid expansion and devoid of cash. Their CR-2000 device (for research only) continues to sell well; the exposure they receive with this, especially with physicians who conduct research while maintaining a clinical practice, has given them an invaluable foot-in-the-door for the introduction of the now clinically approved device. This, along with the recent selection by Pfizer to use the CR-2000 in a large, nationwide study, continues to give the company exposure precisely in the market where it intends to sell the clinical profilor. Consistent with the tone of the entire conversation, the spokesman made no specific leading comments regarding strategic partners for marketing (even when pressed regarding Pfizer) other than to state they were proceeding in a controlled fashion and will have announcements in the near future. This information is obvious severely tinted by the viewpoint of the company; such a perspective demands extreme caution and overriding skepticism. Nevertheless, I was pleased with their conservative approach towards the future. I hope this helps. Good luck. Scott