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Biotech / Medical : ICOS Corporation -- Ignore unavailable to you. Want to Upgrade?


To: Ian@SI who wrote (796)11/29/2000 9:28:05 PM
From: Ian@SI  Read Replies (1) | Respond to of 1139
 
DJ Newswires picks up coverage of IC 351 or Cialis....

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November 29, 2000

Lilly, Icos Say Drug Cialis Shows
Promise as Pill to Treat Impotence

Dow Jones Newswires

WASHINGTON -- Following the trail of little blue Viagra pills that
single-handedly ignited the impotence market, Eli Lilly & Co. and partner
Icos Corp. announced positive results of their own treatment for erectile
dysfunction.

The pill, Cialis, helped three times as many impotent men than a sugar pill
did in an intermediate study of 212 men.

The research, which found that 88% of men taking Cialis had improved
erections compared with 28% of men who were given a inactive sugar pill,
will be presented at the Ninth World Meeting on Impotence Research in
Perth, Australia.

Now the drug is being tested in larger studies and the companies plan to
submit an application to the Food and Drug Administration in the second
half of 2001 to have the drug approved for sale in the U.S.

Cialis, like Pfizer Inc.'s Viagra, works to relax the smooth muscles in the
penis to allow blood to flow in so that men can achieve and maintain an
erection.

Alex Zisson, pharmaceutical analyst at Chase H&Q, said there should be
room for Cialis in the market dominated by Viagra, which grabbed $332
million in sales for the third quarter.

"Cialis looks very, very similar to Viagra," Mr. Zisson said. "There is no
market, especially a billion-dollar market, that is fully satisfied by one drug.
The second and third drugs usually expand the market."

In the studies, Cialis users haven't complained about experiencing bluish
tints in their vision, a side effect reported by Viagra users. This could
encourage some users to favor Cialis, if indeed it produces fewer side
effects
, the analyst said.

Although there hasn't been a head-to-head study comparing Cialis to
Viagra, Dr. Albert Yu, senior director of clinical research at Icos, said
Cialis is more potent and more selective than Viagra.