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To: J.R.S. who wrote (3374)	1/8/2001 9:53:44 AM
From: Rande Is	Read Replies (1) \| Respond to of 4766

Integrated Surgical Systems Receives an Order for Two ROBODOC(R) SurgicalAssistant Systems From Japan DAVIS, Calif., Jan. 8 /PRNewswire/ -- Integrated Surgical Systems, Inc. (ISS) (Nasdaq: RDOC; Easdaq), a pioneer in medical robotics and the world leader in image-directed, semi-autonomous robotic products for surgical applications, announced today that it has received an order for two (2) ROBODOC Surgical Assistant Systems (ROBODOC) from Imatron-Japan, its Japanese distributor. (Photo: NewsCom: newscom.com The first system is scheduled for delivery in January 2001 and the other in March. Ms. Kinoshita, the President of Imatron-Japan stated that, "There is so much interest in the ROBODOC System in Japan that we anticipate installing many more systems in 2001 and beyond. The surgeons, who have had the opportunity to observe a surgery either here or in Germany, are absolutely convinced of the technology and it's clinical potential. This base is now growing." Three ROBODOC Systems have already been installed. With one system already in Japan and two systems being delivered this quarter, a total of (6) six ROBODOC Systems will be operating in Japan by the second quarter. "We had expected Japan to be one of our major markets for both the ROBODOC and the NeuroMate Systems. This order coupled with the recent order for (6) six NeuroMate Systems are strong indications of that market potential," commented Dr. Ramesh Trivedi, President and CEO of Integrated Surgical Systems. The Products: ROBODOC is the robotic surgery system of ISS that is used for total joint arthoplasties. ROBODOC consists of a robotic arm assembly and a PC-based 3-D planning station called ORTHODOC(R). ISS has installed 37 ROBODOC systems worldwide. The ISS neurosurgery product, NeuroMate(TM), is the first robotic technology based system for use in stereotactic brain surgery. NeuroMate consists of a robotic arm assembly and a PC-based planning system. NeuroMate also interfaces with other popular planning stations offered by third-party vendors. ISS has installed 16 NeuroMate systems in the U.S., Europe, and Japan. The Company: Integrated Surgical Systems, Inc. develops, manufactures, markets and services computer-controlled, image-directed robotic products for surgical applications. ISS produces the ROBODOC Surgical Assistant System (ROBODOC), which is designed for orthopedic applications. The ROBODOC System has been used to perform successful total hip replacement surgeries on more than 7,300 patients worldwide. ROBODOC is currently being marketed in Europe and the Middle East. NeuroMate(TM), an ISS neurosurgery product, is the first robotic technology for use in stereotactic brain surgery and it has supported to date over 3,000 neurosurgical procedures. Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including the timely development and market acceptance of new products and upgrades to existing products, the impact of competitive products and pricing, and other risks detailed from time to time in the company's filings with the Securities and Exchange Commission (SEC). NOTE: ROBODOC(R) is a registered trademark of Integrated Surgical Systems, Inc. NeuroMate(TM) is a trademark of Integrated Surgical Systems, S.A. For more information on Integrated Surgical Systems via fax at no cost, please call 800-PRO-INFO or 732-544-2850 outside the USA, ticker symbol RDOC