SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?


To: Biomaven who wrote (2844)2/7/2001 2:42:51 PM
From: scaram(o)uche  Respond to of 52153
 
Agreed for a Phase I, but this is a Phase Ib - they've presumably already determined the MTD in Phase I and now
all they are likely doing is looking at multiple dose PK etc.

FWIW, here is the SCIO announcement on their Phase I results:.........


Ah, got it. Thanks. Went back and reread the initial question, and see that it applies to the projected transition from Ib, not the speed of transition to it.

Like I said, I know nada re. SCIO. Stopped following them at the second name change.



To: Biomaven who wrote (2844)2/7/2001 4:00:21 PM
From: Biomaven  Read Replies (1) | Respond to of 52153
 
for a cumulative probability of a compound entering Phase I of about 15%.

Thanks to lrb for pointing out that those probabilities actually multiply to about 22%, not 15%. (One too many .7 in my multiplication!).

So that should be a little better than a 1 in 5 shot of ultimate success for a candidate just entering Phase 1.

Peter

P.S. Unless of course you need to add back that .7 these days for the chance of withdrawal after approval. <g>