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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?


To: Mark Bong who wrote (2979)2/24/2001 7:57:59 PM
From: Mike McFarland  Respond to of 52153
 
Nature 409, 818 - 820
pseudogenes--fragments of genes



To: Mark Bong who wrote (2979)2/24/2001 10:22:32 PM
From: Torben Noerup Nielsen  Respond to of 52153
 
Interesting. I'm betting on the cDNA. The definition of a gene has become too vague. But proteins are well-defined and so are the cDNA sequences that encode them.



To: Mark Bong who wrote (2979)2/25/2001 8:28:15 AM
From: Biotech Jim  Read Replies (1) | Respond to of 52153
 
Mark-

I do have several of the skills to decide on the real number of genes expressed by the human genome. From my own work and the evaluation of at least two databases using *cDNAs as assessed by cloning work, and the corresponding mRNAs as assessed by microarray and/or pcr analysis*, my bet is that there is between 75,000 to 100,000 mRNAs and consequently proteins expressed from the human genome. I would also not bet against Haseltine.

Jim