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Biotech / Medical : The thread of life -- Ignore unavailable to you. Want to Upgrade?

To: nigel bates who wrote (99)	3/7/2001 5:16:49 PM
From: Mike McFarland	Read Replies (1) \| Respond to of 1336

100! Ah, satisfying. MLNM March 35 calls can be had for less than a buck, could it be a good bet, is the next fomc meeting before options expiration this month? Actually, I do not care, just making noise and claiming the 100th post for myself. Maybe I should close the thread and start: Voyage of the Dawn Trader heh! ScienceWeek this week: 4. EVOLUTIONARY BIOLOGY: A CRITIQUE OF THE COEVOLUTION THEORY OF THE GENETIC CODE The "code coevolution" hypothesis proposes that the genetic code coevolved with the evolution of biosynthetic pathways for new amino acids. A re-examination of the biochemical basis of the genetic code coevolution theory to test the validity of its statistical support demonstrates that the theory's definition of "precursor-product" amino acid pairs is unjustified biochemically because it requires the energetically unfavorable reversal of steps in extant metabolic pathways to achieve desired relationships. In addition, it is suggested that coevolution theory neglects important biochemical constraints when calculating the probability that chance could assign precursor-product amino acids to contiguous codons. The authors report a conservative correction for these errors reveals a suprisingly high 23 percent probability that apparent patterns within the code are caused purely by chance. (T.A. Ronneberg et al:Proc. Natl. Acad. Sci. US 5 Dec 00 97:13690) Abridged from ScienceWeek scienceweek.com