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To: Junkyardawg who wrote (6202)3/22/2001 5:21:39 PM
From: Original Mad Dog  Respond to of 15481
 
Enbrel tests halted chronic heart failure treatment
SEATTLE, March 22 (Reuters) - Drug maker Immunex Corp. (NASDAQ:IMNX) said on Thursday said it will not proceed with phase 2 and 3 testing of its drug Enbrel for treatment of chronic heart failure, but the drug shows positive results in psoriatic arthritis patients.

Seattle-based Immunex said it made the decision to stop testing for Enbrel for treatment of chronic heart failure after guidance from an independent data monitoring board indicated the drug, "would not be able to meet efficacy end-points."

"Future development decisions for Enbrel in chronic heart failure will be made after we have complete analysis of all data from these studies," said Leslie Garrison, Immunex senior vice president of clinical development.

But Immunex and Wyeth-Ayerst Laboratories, a division of American Home Products Corp. (NYSE:AHP), said psoriatic arthritis patients receiving Enbrel experienced "significant improvement in signs and symptoms of their disease compared to placebo."

Based on these results, the company plans to file a supplemental biological license application with the U.S. Food and Drug Administration in mid-2001, the companies said.