To: 2MAR$ who wrote (1393 ) 6/26/2001 9:07:42 AM From: 2MAR$ Respond to of 208838 ICOS Files Shelf Registration Statement BOTHELL, Wash., Jun 25, 2001 (BUSINESS WIRE) -- ICOS Corporation (Nasdaq:ICOS) announced today that it has filed with the Securities and Exchange Commission a universal shelf registration statement on Form S-3 which, when declared effective, will permit ICOS, from time to time, to offer and sell common stock, par value $0.01 per share, debt securities and convertible debt securities, up to a total value of $300,000,000. ICOS is a product-driven company that has expertise in both protein-based and small molecule therapeutics. ICOS combines its capabilities in molecular, cellular and structural biology, high throughput drug screening, medicinal chemistry and genomics to develop highly innovative products with significant commercial potential. ICOS applies its integrated approach to specific target areas where it has expertise. ICOS believes this strategy increases its chances of successfully developing commercial products. A registration statement relating to these securities has been filed with the Securities and Exchange Commission but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective. This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements involve risks and uncertainties that could cause ICOS' results and the timing of certain events to differ materially from those discussed in the forward-looking statements, including risks associated with clinical development, regulatory approvals, product commercialization, intellectual property claims and litigation and other risks detailed in ICOS' latest Annual Report on Form 10-K and its other public filings filed with the Securities and Exchange Commission. businesswire.com CONTACT: ICOS Corporation Lacy Fitzpatrick, 425/415-2207 URL: businesswire.com