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To: Frederick Langford who wrote (11305)6/29/2001 2:56:10 PM
From: Tom Hua  Read Replies (1) | Respond to of 19633
 
Fred, will do although XLNX has shown to be a difficult short, there's just too much institutional support.

On another subject, here's the BW article on AVAN.

Regards,

Tom

JULY 9, 2001

INSIDE WALL STREET

Good Medicine at Avant

Why would Pfizer, Merck, Bristol-Myers Squibb, or
Novartis be interested in obscure Avant
Immunotherapeutics (AVAN )? Answer: products in
trial that target multibillion-dollar
markets--cholesterol management, cardiac surgery,
and vaccines for cholera and typhoid.

Avant is in talks for a partner in cholesterol
management, and it could be Pfizer, Merck, or
Bristol-Myers. Avant has a novel vaccine in Phase 2
trials that seeks to raise the levels of high-density
lipoprotein (HDL), the so-called good cholesterol.
Low levels of HDL are associated with greater risk
for atherosclerosis, or hardening of the arteries,
which leads to heart disease and strokes. This
vaccine alone targets a $4 billion market, says a
money manager who owns some 3% of Avant. The
company expects the vaccine to be on the market by
2006. In cardiac surgery, Avant's lead compound,
TP-10, now in Phase 3 clinical trials, treats injury
that occurs during surgery. Avant has received
fast-track-approval status from the Food & Drug
Administration for the use of TP-10 in infants
undergoing surgery. Avant has a deal with Novartis
to develop TP-10, due out by 2006, with a potential market of $1 billion.

Mark Monane of investment firm Needham rates Avant, now trading at 5, a
"strong buy," based on its products that "address large market opportunities for
which current therapies are inadequate." His 12-month price target: 10.

By Gene G. Marcial