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Biotech / Medical : Bioterrorism -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (439)11/10/2001 12:39:16 AM
From: Jon Koplik  Respond to of 891
 
AP News -- Old Smallpox Vaccines May Still Help

November 9, 2001

Old Smallpox Vaccines May Still Help

By THE ASSOCIATED PRESS

Filed at 5:12 p.m. ET

ATLANTA (AP) -- With the anthrax scare stirring fears of a far deadlier
smallpox attack, health officials are trying to reassure the public that people
vaccinated decades ago are probably still protected.

The government has 15.4 million doses of smallpox vaccine and wants to buy
300 million more, enough to vaccinate the entire country. However, there are no
government plans for a mass vaccination.

Health experts say the immune systems of people who received multiple shots
before the government ended smallpox vaccinations in 1972 can probably still
fight the disease.

Before the program ended, children were immunized as toddlers and usually again
when they started school. And international travelers were required to show
proof of a recent vaccination.

``If someone has had three immunizations, it would offer a significant degree of
protection for decades,'' said Dr. Harry L. Keyserling, a smallpox expert at
Emory University.

Research on smallpox outbreaks from the early 1900s shows the disease killed
only 10 percent of people who had been vaccinated as much as 50 years before.

The Centers for Disease Control and Prevention's bioterrorism Web site says the
level of immunity left in people vaccinated before 1972 is uncertain. And the
CDC conservatively warns the vaccine is most effective for three to five years.

But the agency is revising its guidelines to let state health departments know
about the vaccine's lingering protection, said Dr. James LeDuc, acting head of
the agency's viral division.

The government opposes mass vaccinations because it believes they are
unnecessary and because the vaccine can cause crippling side effects.

Smallpox was declared eradicated worldwide in 1980, but the virus is stored in
government laboratories in a few places around the world.

The virus is contagious and deadly, killing three in 10 of its victims. But experts
say that a smallpox attack is unlikely to unleash a doomsday outbreak that could
instantly get out of control.

There is a window of up to 11 days between the time people contract the virus
and the time they actually become sick and develop the scabs that make the
disease contagious.

Particularly in a time of heightened alert, doctors say they would probably be able
to recognize a small outbreak during that window and quickly vaccinate people
who came in contact with the victims.

``It has a rather slow evolution,'' LeDuc said. ``We think it's not going to be a
wildfire.''

Smallpox is among the bioterrorism agents the CDC has warned doctors to
watch for since the Sept. 11 attacks. No case has been documented in the United
States since 1949.

Health officials have never stopped testing the effectiveness of the U.S. stockpile
of vaccine and said they are confident it would work.

``The stuff is incredibly stable,'' LeDuc said.

Copyright 2001 The Associated Press