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Politics : Sharks in the Septic Tank -- Ignore unavailable to you. Want to Upgrade?


To: thames_sider who wrote (37069)11/16/2001 9:34:15 AM
From: Lane3  Respond to of 82486
 
Is that from bearing children, or from breast-feeding?

<<Parity (having children) and the age of the woman at the birth of her first offspring are other enodgenous hormonal factors that influence breast cancer. Women who have never had children (nulliparous) are at greater risk for the development of breast cancer than women who have had children (parous), with a risk factor of approximately 1.4. The effect of term pregnancy on breast cancer risk varies with the age of the mother's first birth, with women whose first pregnancy occurs after age 30 having a 2-5 fold increase in breast cancer risk compared with women having a first term pregnancy before age 18 or 19. Abortion, whether spontaneous or induced, before full-term pregnancy, appears to have no protective effect. In some studies, premature termination of pregnancy appears to increase breast cancer risk. This apparent contradiction might be explained by the sustained level of hormones in a term pregnancy. Breast tissue may undergo differentiation as a result of hormonal changes of pregnancy. These differentiated cells are less likely to undergo malignant transformation. In incomplete pregnancy, the breast is exposed only to the high estrogen levels of early pregnancy and thus may be responsible for the increase risk seen in these women.>>

cancer.med.upenn.edu