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To: scaram(o)uche who wrote (646)11/29/2001 10:40:07 AM
From: scaram(o)uche  Read Replies (1) | Respond to of 1833
 
Damn it, look at what can be done with functional genomics and $25 million!!!!!!!!!

Sheeesh......... Glass............ hell has frozen over, pigs have flown, etc.

Thursday November 29, 10:22 am Eastern Time

Press Release

SOURCE: The Institute for Genomic Research

TIGR Develops Major Center for Functional
Genomics with $25 Million Contract From the
National Institute of Allergy and Infectious Diseases

ROCKVILLE, Md., Nov. 29 /PRNewswire/ -- Now that many of the genomes of organisms
associated with the leading causes of infectious diseases have been sequenced, the next major
challenge is to determine the biological function of genes and the proteins they produce. This
is a challenge for both biology and technology. But functional genomics resources for the
production and utilization of DNA arrays and genotyping activities remain prohibitively
expensive for many researchers to set up or access.

Therefore, the National Institute of Allergy and Infectious Diseases has awarded a $25
million/five year contract to The Institute for Genomic Research (TIGR) to establish a center
for functional genomics that will be an invaluable resource to the scientific community. This
contract reflects the NIAID's commitment to enabling advances in this critical area of
research.

``TIGR is extremely pleased to receive this contract from NIAID. It will allow us to continue
our work at the forefront of genomics while also providing a unique service to the scientific
community,'' says TIGR president Claire M. Fraser, Ph.D. ``Because of the collaborative
nature of the partnership the new Center will have with its clients, we believe that novel ideas
will be generated to help us reach our goal of finding new research tools as well as practical
solutions to microbial diseases.''

The Pathogen Functional Genomics Resource Center (PFGRC) at TIGR will centralize
production, access, and training in the use of a variety of resources for exploring the roles of
genes and gene products (including proteins) in a significant number of microbes known to
cause disease. It will be a multidisciplinary laboratory, resource, and teaching facility.

The Pathogen Functional Genomics Resource Center at TIGR will provide scientists with
centralized resources necessary to conduct functional genomics studies on a variety of
pathogens and vectors for which genomic sequence information is currently, or will soon be,
available. The near-term goals of the PFGRC are to provide researchers with microarray and
genotyping technology, along with access to clone sets, genomic DNA, and type strains.
TIGR's strong bioinformatics capacity will provide the resources for data analysis and
storage. The new PFGRC will develop a Center-Client web-based interface that will make it easy for scientists to access and
acquire resources. Information on the plans for the PFGRC can be found on the world wide web at pfgrc.tigr.org .

These new technologies in functional genomics hold great promise for identifying the roles played by the thousands of novel but
as yet uncharacterized genes that have been revealed by genome sequencing, and for unraveling the complex relationships
among genes. While such research will dramatically increase our understanding of the basic biology of pathogenic organisms, it
should also accelerate the identification of new diagnostic markers of infectious disease, new therapeutic targets, and new
vaccine candidates. The importance of such anticipated advances cannot be overemphasized. Infectious and parasitic diseases
are the second leading cause of death world-wide and increasing levels of antibiotic resistance are posing ever-increasing
threats to public health.

TIGR is an ideal home for the Pathogen Functional Genomics Resource Center. The Institute is widely recognized as a leader in
all aspects of genomics, including sequencing, and functional, and comparative genomics. In 1995 TIGR scientists were the first
to publish the complete sequence of a free-living organism, Haemophilus influenzae. Since its founding as a not- for-profit
research institution in 1992, TIGR scientists have sequenced the complete genomes or chromosomes of more than 25
significant organisms, including those that cause cholera, tuberculosis, chlamydial infections, and syphilis. TIGR scientists are
also active in research projects on agriculturally important organisms, and are leaders in studying so-called ``extremophiles,''
that survive under conditions that are not compatible with human life, but reveal important information about biological
evolution.

Press releases and other material related to TIGR are available at tigr.org .

SOURCE: The Institute for Genomic Research