To: EL KABONG!!! who wrote (6 ) 5/9/2003 12:55:03 PM From: Alastair McIntosh Read Replies (1) | Respond to of 261 Re: Mexicans Angered by Spread of Corn You may not be aware that Nature subsequently admitted that the available evidence did not justify publication of the study.whybiotech.com The editors of Nature yesterday admitted having made a mistake in publishing a controversial study that claimed wayward genes from genetically modified corn contaminated maize in remote regions of Mexico. But they could not quite bring them to say 'we were wrong.' The study, which was published in November and made headlines around the world, said the Mexican maize carried transgenes that could only have come from genetically engineered crops. Now, Nature editor Philip Campbell says the evidence was "not sufficient to justify the publication of the original paper." But since the scientists wish to stand by their conclusions, Campbell says "we feel it best simply" to make the circumstances clear, "and allow our readers to judge the science for themselves." "They're copping out," says Matthew Metz, a geneticist at the University of Washington in Seattle, who was horrified when he read the study by David Quist and Ignacio Chapela of the University of California Berkeley in November. It was riddled with errors and came to "outrageous conclusions" not backed by the data, Metz says. Metz, and several others, sent detailed rebuttals to Nature, two of which the journal published online yesterday, along with Campbell's statement. Metz says the Quist and Chapela study was "a testament to technical incompetence" and says he was amazed it ever got past Nature peer reviewers, who vet studies before publication. Quist and Chapela misinterpreted and misread the genetic "artefacts" they saw in the Mexican maize, Metz and others say. "They failed to carefully scrutinize their own data, and it would seem that an ideological conflict encouraged this lapse in scientific integrity," says Metz, who describes Quist and Chapela as "fervent anti-genetic engineering activists." Metz, who has been called pro-GM, collaborates with a biotechnology company devising new plants in Seattle. Six geneticists from the U.S. Department of Agriculture and the University of California support Metz' view. In their rebuttal in Nature, they say most of the transgenes Quist and Chapela claimed to have found in native maize in Oaxaca, Mexico, came from their own experiments and a misreading of their data. "Transgenic corn may be being grown illegally in Mexico, but Quist and Chapela's claim that these transgenes have pervaded the entire native maize genome is unfounded," the geneticists say. Quist and Chapela are not about to back down. They admit to making mistakes. The criticism they misidentified some gene fragments in their experiments "is valid," they say. But they say new data "confirms our original detection of transgenic DNA integrated into the genomes of local landraces [of maize] in Oaxaca." The new evidence is not, however, enough to convince Nature. "The authors have now obtained some additional data, but there is disagreement between them and a referee as to whether these results significantly bolster their argument," says Campbell. "In light of these discussions and the diverse advice received, Nature has concluded the evidence available is not sufficient to justify the publication of the original paper."