To: oldirtybastard who wrote (8938 ) 1/16/2002 3:12:09 PM From: Sir Auric Goldfinger Read Replies (3) | Respond to of 19428 VVUS 4 Ice Queens! (the pig has arisen from the dead): SMARTMONEY.COM: One-Day Wonder: The Female Viagra? 2001-12-14 17:58 (New York) By Lawrence Carrel Of SMARTMONEY.COM - ---------------------------------------------- Vivus (VVUS) Share price as of Thursday's close: $3.99 Share price now: $5.46 Change: 36.8% Volume: 3.6 million shares, daily average 108,200 Last time this high: Aug. 11, 2000 52-week high: $5.25 52-week low: $1.590 Forward P/E before announcement: n/a Forward P/E after announcement: n/a - ---------------------------------------------- FORGET ABOUT BUILDING a better mousetrap. Remembering what Viagra did for Pfizer (PFE), investors beat a path to Vivus's (VVUS) door Friday on news that the company has developed a treatment for female sexual dysfunction. The stock rose 37% after Ken Trbovich, an analyst at C.E. Unterberg Towbin, trumpeted the drug and raised his rating to Strong Buy from Buy. Vivus has been down this road before. It was one of the first companies to come up with an effective treatment for male impotence. But the process proved too invasive for most men, and the company got sidelined by Pfizer and its Viagra. This time, though, companies with rival pharmaceutical solutions for female sexual dysfunction - such as Pfizer and Eli Lilly (LLY) ICOS (ICOS) joint venture - have failed to demonstrate benefits in early trials. While those companies relied on pills, Vivus's Alista is a topical treatment believed to increase blood flow to the female genitalia. Trbovich's rating is based on positive results from a Phase II study of Alista as reported by the company in a Nov. 29 press release. The actual data from the study won't be released until May. But Vivus said the study found statistically significant differences between the responses to Alista and a placebo among 79 patients. Although the drug needs to go through many more trials, and won't become commercially available before 2005, Trbovich focused on the positives. There's now no product to treat female sexual dysfunction, which is reported to some degree by 43% of all women. That compares with the 31% of men who suffer from some form of erectile dysfunction, and who currently comprise a $1.5 billion market. Quote "We previously ignored the potential value of Alista due to the lack of supporting clinical evidence," wrote Ken Trbovich in his report Friday. "Now, Alista appears to be Vivus's lead compound. On its own, Alista could be worth $5 per share, nearly the value we assign to Vivus's other compounds combined." For more information and analysis of companies and mutual funds, visit SmartMoney.com at smartmoney.com .