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Strategies & Market Trends : Booms, Busts, and Recoveries -- Ignore unavailable to you. Want to Upgrade?

To: Maurice Winn who wrote (14419)	2/4/2002 3:10:16 PM
From: LLCF	Read Replies (1) \| Respond to of 74559

LOL, agreed, brain stuff makes the marekt! However... speaking of the market, the head watchdog [SEC chairman Pitt] won't take oath for his testimony??? Then there's this: Message 17008437 Intersting that the 'market' turns out to be the freakin KAZBAH with like zero transparency... or perhaps the transparancy of a third world market. DAK

To: Maurice Winn who wrote (14419)	2/4/2002 4:35:53 PM
From: Ilaine	Read Replies (1) \| Respond to of 74559

Re: neutransmitters - the brand of melatonin you take matters - try TwinLab. Also, you may get good results adding in some GABA - for brand, I like Solgar, 500 mg. Good sleep is one of the most important things in life. If only the bad guys had consciences, they'd be good so they could sleep at night.

To: Maurice Winn who wrote (14419)	2/4/2002 6:30:31 PM
From: Snowshoe	Respond to of 74559

This brain stuff is exactly on topic DJ. It's what makes the market. Literally, perhaps. A few years ago some wag put out a chart showing a very strong correlation between Prozac sales and the rise of the stock market. I suppose the relationship may still be true today if one used Prozac profits instead of sales, given the proliferation of Prozac competitors.

To: Maurice Winn who wrote (14419)	2/4/2002 8:23:11 PM
From: TobagoJack	Read Replies (1) \| Respond to of 74559

Hi Maurice, <<If we can just get the right chemical balance in everyones' heads, we'll have the Dow at 100,000 in no time and we'll all be rich!>> Precisely wrong, and very definitely upside down! With DOW at 100,000, a cup of coffee will be at USD 100. OTOH, with the DOW at 5000, we could be rich, especially when resetting our MS Money program base currency to Q. Chugs, Jay

To: Maurice Winn who wrote (14419)	2/5/2002 7:40:35 AM
From: smolejv@gmx.net	Respond to of 74559

>>This brain stuff is exactly on topic DJ. It's what makes the market. << Duh. Next comes "no-brand Prozac copycats reponsible for market collapse. Ecstasy as a fall-back measure?". Snap out of it, Mq. Here's something fresh on addiction - Sex, Drugs, Rock&Roll and QCOM (AG? - no, that one is tough) as possible targets. Just want help some of the readers kick the habit (). dj ---------- : will not mention any names, to avoid getting Mq pd. ---------------------- Phenotype Offers New Perception on Cocaine* - Researchers say glutamate is more essential to addiction than dopamine In cocaine research, dopamine and glutamate make a brilliant star and supporting player, respectively. One takes center stage, the anointed crowd-pleaser; the other, though a leading actor in other productions, is so overshadowed that admiration of its performance is relegated to an acquired taste. A quick PubMed search recently disclosed their perceived importance; 3,628 abstracts on cocaine and dopamine, 178 for cocaine and glutamate. ....[he] began the self-administration experiments by first training knockout and wild type mice to press a lever in order to get food. Both groups learned lever pressing equally well. Then he substituted intravenous cocaine for food and watched what happened. Wild type mice responded enthusiastically to the new menu, and would press for cocaine a dozen or more times an hour. mGluR5 mutants ignored cocaine at every dose; within a few sessions they would learn levers no longer produced food and stop pressing. ... Conquet does not know if mGluR5 plays a role with ethanol and nicotine addiction. Self-administration experiments have not been done. Partly he hasn't had time, since he's busy starting Addex. Partly the mice haven't had time, since other drugs of abuse, especially alcohol, require longer training periods. Whether mGluR5 influences other so-called addictions, is a question left for the distant future. If Addex does find a good mGluR5 antagonist, therapeutic possibilities may extend well beyond helping snorters and crackheads stay clean. Glutamate may be implicated in numerous psychiatric disorders, according to Kalivas. mGluR5 inhibitors have been suggested as possible treatments for Alzheimer Disease, Parkinsonian akinesia, muscle rigidity, stroke, anxiety, and inflammatory pain. But as always, Kalivas reminds, once a good drug candidate is in hand, only running the clinical experiments will tell for sure. References 1. C. Chiamulera et al., "Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice," Nature Neuroscience, 4:873-4, September 2001. 2. Z. Jia et al, "Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory," Physiology and Behavior, 73:793-802, August 2001. 3. C.j. Swanson et al., "Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation:a potential role for Homer," journal of Neuroscience, 21:9043-52 Nov 15 2001