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To: axial who wrote (8751)	2/12/2002 10:48:53 PM
From: Mark Bartlett	Respond to of 14101

Hi Jim, <<Joyce Mueller.>> During my DD, I emailed her. She was very nice and had nothing but good things to say about Dr. Jacob and her Tx with DMSO. MB

To: axial who wrote (8751)	2/13/2002 12:28:20 AM
From: Cal Gary	Read Replies (1) \| Respond to of 14101

Wonderful Post on SH Jim! I hope you don't mind that I snip and tuck it here. But here's the rub: HC professes to offer a service to both the people of Canada, and the companies it regulates. It obtains funding from both of these sources. It proposes deadlines that it does not meet, and after it fails to meet them, it then requires the "regulated" company to jump through more nonessential hoops. Presumably this expensive process will be repeated until FDA approval is/is not granted. I'm not the first on this thread to propose this: why don't we just link to approval by others, and dispense with this expensive and wasteful sham? I am not disagreeing with the sense of your post. What I'm asking is: if what you say is true, why should we pay, as investors and taxpayers, for a service that HC, on its own, independent initiative never intends to perform? It's a huge fraud. The entirely reasonable scenario that you have proposed raises as many questions as it answers, unfortunately. Unfortunately, the explanation also does little to change my perception of the possibility of political interference.

To: axial who wrote (8751)	2/13/2002 10:42:00 AM
From: Joe Krupa	Respond to of 14101

Hi Jim, Some interesting research facts from the Ortho-McNeil (J&J) website: ortho-mcneil.com The National Council on the Aging. Pain and Older Americans Survey -- Major Findings -- One in five Americans over age 60 takes medication to control pain that lasts for six months or more (chronic pain). This represents 18% of Americans in this age group, or 7.5 million people. The majority of seniors who take pain medication believe it is effective in controlling pain. Nine in ten (89%) who take prescription pain medication say it is effective, and 85% of those who take over-the-counter pain drugs say medication is effective. Two out of three older Americans who take pain medication (64%, or 4.7 million) say pain still prevents them from performing routine tasks, engaging in hobbies, or doing other activities they enjoy. Of these, 44% say pain interferes with their ability to walk, 17% say pain prevents them from accomplishing daily activities such as housework and cooking, and 14% say pain prevents them from socializing or doing hobbies such as gardening. One in three (31%) say pain prevents them from performing other non-specified activities of daily living. Older Americans who take pain medication are more likely to suffer from arthritis (44%), bone and joint pain (31%), and low back pain (16%) than any other type of pain condition. The most commonly used prescription medication for treating the leading causes of pain (arthritis, bone and joint pain, and low back pain) was non-steroidal anti-inflammatory drugs (NSAIDs, e.g., ibuprofen and naproxen). 18% of survey respondents took NSAIDs to treat their pain, while 10% took propoxyphenes, 5% took codeine derivatives (e.g. hydrocodone), and another 5% took codeine combined with aspirin or acetaminophen. More than seven in ten seniors take over-the-counter pain relievers. These are most likely to take acetaminophen (63%), followed by non-prescription NSAIDs (37%) and aspirin (33%). One in five (21%) seniors who take pain medication have also tried alternative pain therapy, such as relaxation therapy, herbal remedies, or TENS (transcutaneous electrical nerve stimulation). One in four (26%) seniors who takes pain drugs experiences side effects caused by the medication. Of these, half say side effects are severe. One in ten say they have been hospitalized as a result. The most common side effects experienced by older people who take pain drugs are drowsiness (20%), dizziness (18%), and indigestion or gastrointestinal disorders (17%). Other common side effects of pain medication are nausea/vomiting/diarrhea (13%), and constipation (12%). More than one in ten seniors who take NSAIDs have ulcers (13%), and 4% are hospitalized because of side effects caused by their pain drug. Among those who have side effects stemming from non-prescription NSAIDs, 7% are hospitalized. Seniors who take prescription pain drugs are likely to do so for a long period of time. Six in ten who use non-steroidal anti-inflammatory drugs (NSAIDs) take them for six months or more despite warnings against long-term use. Seniors are likely to take non-prescription pain medication far longer. On average, seniors who take acetaminophen, over-the-counter NSAIDs, and aspirin take them for five years. Fifteen percent take them for more than 20 years. A majority (68%) who take non-prescription pain relievers take them either daily, or several times a week. Six in ten (58%) seniors who take pain drugs also take medication for non-pain-related medical disorders. Of these, nearly half (47%) take medication to manage high blood pressure. Half of seniors surveyed (48%, or 3.5 million) say doctors don't tell them about possible harmful interactions between pain drugs and other medications they take. Four in ten seniors (37%, or 2.7 million) say doctors don't discuss the potential side effects of the pain drugs they prescribe or recommend. Americans over 60 who take pain drugs are most likely to consult at least three different doctors about their pain conditions. Eight in ten (79%) see primary care physicians, compared to 17% who see orthopedists, 9% who see rheumatalogists, and 6% who see neurologists. The Pain & Older Americans Survey was conducted by Louis Harris and Associates, Inc. on behalf of The National Council of the Aging, Inc. It is a survey of a national cross-section of 500 randomly selected Americans over age 60 who regularly take pain medication prescribed or recommended by a doctor for pain medications lasting six months or longer. The survey was underwritten by an educational grant from Ortho-McNeil Pharmaceutical.