SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Indications -- Psoriasis/Chronic Inflammation -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (167)2/21/2002 12:48:17 AM
From: Miljenko Zuanic  Read Replies (1) | Respond to of 631
 
<<AGIX-4207 is a selective modulator of TNF-alpha induced redox-sensitive inflammatory genes.>>

What are those genes (c-fos, c-jun,..)? How are their expression related to TNF, and what other cytokines may induce over-expression? How 4207 control downstream TNF activity, mechanisms, and what about selectivity?

TIA,

Miljenko