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Biotech / Medical : Illumina (ILMN) Optics for Genomics -- Ignore unavailable to you. Want to Upgrade?

To: mopgcw who wrote (21)	3/20/2002 10:46:43 PM
From: mopgcw	Read Replies (1) \| Respond to of 276

Illumina and Oxagen to Collaborate On Fine Mapping of SNP Loci in Genetic Linkage Regions Illumina's BeadArray(TM) Technology to Enable Detailed Exploration of Linkage Regions; Oxagen to Add Potential New Targets to Discovery Pipeline SAN DIEGO & ABINGDON, ENGLAND--(BW HealthWire)--March 19, 2002-- Illumina, Inc. (Nasdaq: ILMN - news) and Oxagen Limited, a private clinical genomics company, announced today that they have signed a collaborative, commercial agreement to generate detailed maps of single nucleotide polymorphism (SNP) clusters in defined chromosomal regions. Under the terms of the agreement, Oxagen will provide a collection of SNP loci within linkage regions together with samples from their extensive library of family collection material and information. Illumina will use its BeadArray technology to design functional assays for the SNPs provided and generate several million overall genotype calls from the sample set. Oxagen will retain rights to all genes and novel associations discovered as a result of the study. Further details about the agreement were not disclosed. Jay Flatley, Illumina President & Chief Executive Officer, noted ``Oxagen is taking a systematic, genome-wide approach to understanding the molecular basis of disease. Dr Nicholls and his team have built a large, proprietary collection of family samples and data, which represent a powerful resource for identifying and validating disease-causing genes. We're looking forward to our relationship with Oxagen, and we're confident that our genotyping capability will provide valuable information that paves the way for the identification of disease genes.'' Dr. Trevor Nicholls, Oxagen Chief Executive Officer, commented ``Oxagen has now created an exceptionally strong base of knowledge in relation to linkage regions relevant to the diseases we are studying. Illumina's BeadArray platform will give us the sample throughput and accuracy we need to extract the maximum information from our valuable samples. Equally important, Illumina's technology is driving down genotyping costs and making feasible large-scale studies like this one. We're very pleased about our collaboration with Illumina and expect that it will allow Oxagen to accelerate its development of improved therapeutic approaches and diagnostic tests.'' About Illumina Illumina (www.illumina.com) is developing next-generation tools that permit large-scale analysis of genetic variation and function. The Company's proprietary BeadArray(TM) technology provides the throughput, cost effectiveness and flexibility necessary to enable researchers in the life sciences and pharmaceutical industries to perform the billions of tests necessary to extract medically valuable information from advances in genomics. Illumina's technology will have applicability across a wide variety of industries beyond life sciences and pharmaceuticals, including agriculture, food, chemicals and petrochemicals. About Oxagen Oxagen (www.oxagen.co.uk) has rapidly established itself as a leading player in the study of complex disease genetics, conducting programs in cardiovascular disease, inflammatory disease and metabolic and endocrine disorders. Oxagen aims to identify new therapeutics and diagnostics by capitalizing on insights from genetics and specializes in using large-scale family studies to understand the association of genes and genetic variations with disease. The Company believes that this approach is the most effective way to provide fundamental insights into the molecular mechanisms of disease. To this end, Oxagen is building its capabilities in functional biology to take forward these discoveries, on its own account and in partnership with major pharmaceutical companies.