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Biotech / Medical : Biotech News -- Ignore unavailable to you. Want to Upgrade?


To: nigel bates who wrote (1592)3/12/2002 11:01:23 PM
From: Jibacoa  Respond to of 7143
 
<<The normal enzyme, which is found in all eukaryotes (animals and plants), is a key antioxidant inside cells, changing potentially damaging "superoxide" molecules into less damaging hydrogen peroxide.>>

Interesting article.

The above was my impression of the role of SOD in playing a "good role" preventing damage during re-vascularization among other things.

Have they found that the altered enzyme SOD1 actually has a deleterious effect on the neurons triggering the changes in ALS ?

If it is just the "association" then could it be possible that the altered enzyme not been able to carry on the antioxidant effect is what may have a role in the pathologic changes ? In that case blocking the Cu access to SOD1 won't make any difference.

I suppose that if they have been working with SOD1 for 10 years, they have enough data to prove that it is indeed a "bad guy" and not an "impaired performer".<g>

Bernard