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To: twentyfirstcenturyfox who wrote (9066)3/20/2002 2:01:10 AM
From: axial  Read Replies (2) | Respond to of 14101
 
Hi, fox -

I reviewed all the posts before investing (well, all the Stockhouse posts, the SI ones later). The Great Garlic Taste Debate was engaged in for quite a while.

It was finally resolved in favor of "No Taste" for Pennsaid.

"1. It is presumably possible for DMSO to carry any other substance on the hands applying Pennsaid transdermally into the body not only to the patient if self applied but also into the body of the applier (if not applied by the patient). Does this create a special danger of unintentionally or intentionally introducing toxic substances into the body when applying Pennsaid and at the very least requiring careful pre application cleansing of hands and also subsequently to application to avoid introducing harmful agents into the body?"

- In a word, yes.

This was part of the whole anti-DMSO hype that I referred to. Particularly in the sixties, it was asserted that DMSO would be the agent by which millions of drug-crazed hippies would introduce unlawful and ungodly substances into their bodies.

There was much made of the fact that the KGB and the CIA could use the substance to poison people, leaving little evidence of the medium by which the poison was introduced.

However, I can also point you to reams of information about people who use DMSO consistently and safely.

These include body-builders, arthritics, animal trainers, and everyday people like you and I, who use it for sprains, bruises, and so on.

DMSO is routinely bought and sold in the United States and Canada - and is widely used, medically, in much of the rest of the world.

dmso.ca

The answers to 2, 3, and 4 are implicit here.
_______________________________________________________

One thing I've wondered about - is Pennsaid offered in a roll-on, as in the site above? And if not, why not?
_______________________________________________________

Yes - long live spirited debate - both sides of the debate.

It's not about winning or losing - it's about the truth: what we accept as proven.

"The real purpose of scientific method is to make sure Nature has not misled you into thinking something you do not actually know..."

Sound evidence, logical and rational thought: that is the basis of science, and the basis of the law.

But hell, if we're talkin' opinions - well, you can say any damned thing you want!

It's when people start confusing opinions with facts, that the debate goes off the rails.

JMO ;- )

Jim



To: twentyfirstcenturyfox who wrote (9066)3/20/2002 7:03:09 AM
From: Mark Bartlett  Read Replies (3) | Respond to of 14101
 
21CF,

To answer your questions.

1) Does this create a special danger of unintentionally or intentionally introducing toxic substances into the body when applying Pennsaid

For DMSO to work as a cellular transport facilitator, the molecules have to be fairly small. I can not remember exactly how many kdaltons, but di7026 posted it some time back on SH. By no means is everything transported across the skin via DMSO - in fact most things are not.

As far as washing ones hands goes, even when you take a pill, your hands should be clean. But in any event, I envision most people using this stuff after they have had a shower and are getting reading for the days OR they are in a washroom and have access to soap and water. If I were going to use it, I'd apply it when I was in a public washroom. Most people have to go at least every 4 hours, so in my own mind that is not a big issue.

Also - the stuff is absorbed very quickly. After applying, a quick wipe would likely do the trick.

2) ...the garlic effect: an inconvenient side effect of DMSO is the presence of a garlic odour and taste in the patient's mouth shortly after application of DMSO.

Non-issue with Pennsaid. I have never heard of one person who has used it complaining of that. I think it got that reputation from those who use industrial grade in copious quantities.

3) Could DMSO be used to conveniently transport narcotics into the body?

Would depend upon the nature of the molecule -- likely yes IMO.

4) (pretend I am Russett:) is there any medical evidence that DMSO is not excreted from the body, quickly, or does it accumulate in the body tissue/organs?

It is excreted quickly via urine and does not accumulate in the body.

5) As to application methods, I suppose that DMX has their reasons for going with the drop method (likely a dosing issue), but a roll-on would seem more convenient.


MB