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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?

To: Spekulatius who wrote (6018)	3/24/2002 2:21:43 PM
From: Miljenko Zuanic	Respond to of 52153

<<Miljenko, does this mean that endostatin gets produced some where in the cascade of events leading to cancer growth?>> Cancer growth....Probably not. My layman view is that E is natural brake or control of the angiogenesis cascade. However, like Angio-1 and Angio-2, it may also have positive and negative effects on angiogenesis??? Depend on the other control mechanisms and cascades of the new vessel growth. Also, in tumor condition when angiogenesis is out of control seams that natural E can do very little to control or suppress further progression. Trials are using very large E doses. This increase problems with side effects, without definite positive therapeutic benefit. Bottom line I do not see E as true anti-angio candidate. Miljenko