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Biotech / Medical : Tularik Inc. (TLRK) -- Ignore unavailable to you. Want to Upgrade?


To: keokalani'nui who wrote (228)6/14/2002 2:49:44 AM
From: Czechsinthemail  Read Replies (1) | Respond to of 598
 
Improvement over dox seems like a reasonable expectation either as improved efficacy or a better side effect profile or hopefully both. Going forward at a higher dosage seems predicated on being able to get more benefit without significant serious side effect. As I recall, they did discuss the shortened dose administration some during the last quarter's conference call. I can't remember the details. What did they have to say about it during the breakout session?

As for the combo trial, I assumed it was in place to explore improvement provided by T67+dox over dox alone. They seem to be confident that T67 will do better than dox, though perhaps not so confident that they didn't want a backup. That was my understanding of the Ph II combo.

I'm looking forward to their announcement of new IND's. Do you have any more info on PPar-g? I'm also curious if they provided more information about potential partnerships. I believe he said they were hoping to announce 1 or 2 more this year.



To: keokalani'nui who wrote (228)6/16/2002 12:19:16 AM
From: Miljenko Zuanic  Respond to of 598
 
<<Not a negative take, but company did not really take on the T67 bear case. >>

What I do not understand why they are continuing with T67 and HCC while so far they have limited and unsatisfactory results???

Miljenko