To: CharlieChina who wrote (55525 ) 7/7/2002 10:21:43 PM From: Swami Respond to of 62348 More stuff just for your information..i hope it doesnt keep you up at night cdc.gov excerpts :- Stockpiling a large number of doses of smallpox vaccine has three major problems. Building a stockpile of 140 million doses might leave public health officials without needed resources to prepare for and implement other interventions, such as quarantine and public education. Second, a large stockpile poses the problem of deciding how to use it. Investing in such a resource may invite the conclusion that the only suitable response to a deliberate release of smallpox would be a mass vaccination campaign, using as much of the stockpile as possible. An enormous logistical problem would be associated with rapidly vaccinating 140 million persons. Assuming 10 minutes per person vaccinated (excluding patient waiting time), 23 million person-hours would be required to vaccinate 140 million people. In 1947 in New York City it took approximately 1 week to vaccinate 6 million people in response to an outbreak with eight cases (1). An additional problem with trying to mass-immunize >100 million people is that, if a transmission rate of 5 is assumed, disease spread might be so rapid as to "outrun" any mass vaccination attempt (Tables 1,2). The third problem associated with a large stockpile of smallpox vaccine is that a large number of side effects would be generated, including need for treatment with vaccinia immunoglobulin and deaths as a result of adverse reactions (26). Between the demands of vaccination and treatment of side effects, the health-care system would be overburdened, to the detriment of treatment for any other disease or medical emergency.