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Biotech / Medical : Tularik Inc. (TLRK) -- Ignore unavailable to you. Want to Upgrade?

To: scaram(o)uche who wrote (321)	10/14/2002 10:55:24 AM
From: scaram(o)uche	Read Replies (2) \| Respond to of 598

United States Patent Application 20020143036 Kind Code A1 Flygare, John A ; et al. October 3, 2002 -------------------------------------------------------------------------------- Pentafluorobenzenesulfonamides and analogs Abstract The invention provides methods and compositions relating to novel pentafluorophenylsulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of the general formula I: 1 -------------------------------------------------------------------------------- Inventors: Flygare, John A; (Burlingame, CA) ; Medina, Julio Cesar; (Belmont, CA) ; Shan, Bei; (Foster City, CA) ; Clark, David Louis; (Albany, CA) ; Rosen, Terry J.; (Burlingame, CA) Correspondence Name and Address: TOWNSEND AND TOWNSEND AND CREW, LLP TWO EMBARCADERO CENTER EIGHTH FLOOR SAN FRANCISCO CA 94111-3834 US Assignee Name and Adress: Tularik Inc. So. San Francisco CA Serial No.: 972743 Series Code: 09 Filed: October 5, 2001 U.S. Current Class: 514/345; 514/352; 514/424; 514/426; 514/518; 514/602 U.S. Class at Publication: 514/345; 514/352; 514/424; 514/426; 514/518; 514/602 Intern'l Class: A61K 031/44; A61K 031/4015; A61K 031/40; A61K 031/255; A61K 031/18 -------------------------------------------------------------------------------- Claims -------------------------------------------------------------------------------- What is claimed is: 1. A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of formula......... (snip)