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To: LPS5 who wrote (469)	1/18/2003 5:08:54 PM
From: RockyBalboa	Respond to of 2534

I remembered a story from a textbook we read in primary school about a Malmoe-based driver who caused an accident under the influence of alcohol but didn't need to go to jail. He was ordered to take a medicine on a daily basis under supervision in order to maintain his freedom and his driving-license. There was no name given for this prescription, only that one would immediately feel very sick after drinking the slighest dose of alcohol. Later I discovered the name of that medicine, its sold as "Antabus", not surprisingly in northern-European countries, like Norway, Sweden, and Denmark - most links point to nordish countries: google.at Its active content, disulfirame mainly inhibits a process named aldehyde-dehydrogenase (oxidating acetaldehyd into acetate, or acetic acide). Acetaldehyde, an oxidation product of Ethyl alcohole is mainly the active substance which gives you the hangover feeling, it is also considered the main cell toxine in connection with the abuse of alcohol. Heavy drinkers and others with liver problems therefore do no longer tolerate alcohol very well because the processes are irreversibly damaged. nlm.nih.gov for a quite scientific description of the impact of alcohol and the adhering biochemical processes see: niaaa.nih.gov