To: twentyfirstcenturyfox who wrote (12004 ) 1/26/2003 1:11:41 PM From: axial Read Replies (1) | Respond to of 14101 Hi, 21CF - There is one point on which I arrive at a completely different conlusion from yours - that is, the importance of the SAP study. It's a study , not a trial. I'm aware of the fact that DMX has begun trials in the past, apparently without informing. I'm not denying the legitimacy of complaints about that. But it's wrong for us to give any credence, in any way, to the notion that this study constitutes an unrevealed trial. More to the point, did anybody seriously expect that the results of WF10 usage would not be monitored, and resultant data captured? That HC will simply say to those using the SAP, "Sure, go ahead!" and then just walk away, without demanding followup data? Or that manufacturers themselves would just throw the drug out to the public, and not have any interest in capturing data on such usage? This is very likely a summary of Greg Pugen's work with WF10 - but we should consider the possibility - however remote - of other physicians' usage. How many times, over and over, have we cautioned on these pages that Greg Pugen's information should be considered anecdotal and does not carry the same weight as trial data? How did it happen, all of a sudden, that this same information became the source of trial data? And not only that, but undisclosed trial data? This study was to be expected. There is nothing unusual about it. The data, on treatment of a wide range of conditions (see:http://www.wf10.com/pages/prevnews.htm and wf10.com - has no protocol, except "Compassionate Use". I can find no reason for suspicion, anger, or accusations relating to the existence of this data. What would make me suspicious? Finding out the data did not exist. Regards, Jim