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Biotech / Medical : Cadus Pharmaceutical Corp. (KDUS) -- Ignore unavailable to you. Want to Upgrade?

To: scaram(o)uche who wrote (970)	2/6/2003 1:18:17 AM
From: scaram(o)uche	Read Replies (2) \| Respond to of 1833

United States Patent Application 20030008380 Kind Code A1 FOWLKES, DANA MERRIMAN ; et al. January 9, 2003 -------------------------------------------------------------------------------- Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor Abstract Yeast cells are engineered to express both a surrogate of a pheromone system protein (e.g., enzymes involved in maturation of .alpha.-factor, transporters of a-factor, pheromone receptors, etc.) and a potential peptide modulator of the surrogate, in such a manner that the inhibition or activation of the surrogate affects a screenable or selectable trait of the yeast cells. Various additional features improve the signal-to-noise ratio of the screening/selection system. -------------------------------------------------------------------------------- Inventors: FOWLKES, DANA MERRIMAN; (CHAPEL HILL, NC) ; BROACH, JIM; (PRINCETON, NJ) ; MANFREDI, JOHN; (NEW YORK, NY) ; KLEIN, CHRISTINE; (NEW YORK, NY) ; MURPHY, ANDREW J.; (MONTCLAIR, NJ) ; PAUL, DR. JEREMY; (SOUTH NYACK, NY) ; TRUEHEART, JOSHUA; (SOUTH NYACK, NY) Correspondence Name and Address: GIULIO A. DECONTI, JR. LAHIVE & COCKFIELD, LLP 28 STATE STREET BOSTON MA 02109 US Serial No.: 309196 Series Code: 09 Filed: May 10, 1999 (for this one, Cadus is not specified as the assignee. however, it was filed on the same day as US2003009022 by the same attorneys.)