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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?

To: keokalani'nui who wrote (7835)	2/6/2003 5:00:04 PM
From: Biomaven	Read Replies (3) \| Respond to of 52153

The drug, known as Gaba Alpha 2/Alpha 3 I don't know much about it at all, but I suspect Reuters got the name garbled. It was apparently a GABA-A a2/a3 agonist. Maybe Biotech Jim (or Neuroinvest) could tell us more. Peter

To: keokalani'nui who wrote (7835)	2/10/2003 11:39:22 AM
From: keokalani'nui	Read Replies (1) \| Respond to of 52153

This is the endothelin receptor antagonist that looked pretty good and was certainly part of abbott's thinking when they acquired Knoll. The postponement of bone pain is consistent with P2. Too bad about TTDP; though it looks like they still have hope to hit TTDP in earlier stage prostate cancer. Dow Jones Business News Abbott Labs Stops Atrasentan Study Monday February 10, 9:18 am ET ABBOTT PARK, Ill. (Dow Jones)--Abbott Laboratories said a preliminary analysis of Atrasentan Phase III data from study MOO-211 in end-stage prostrate cancer patients didn't meet its primary endpoint of time-to-disease progression, and therefore will be stopped. However, the study data showed improvements in development of bone pain as an adverse event, prostate-specific antigen levels, and biochemical markets of skeletal progression in patients taking atrasentan versus placebo, the company said in a press release Monday. Additional Phase III studies in prostrate cancer and Phase II studies in other tumor types will continue. The company said these events won't have an impact on its earnings in 2003 or 2004.