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Biotech / Medical : Biotech Valuation -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (8431)5/20/2003 1:08:09 PM
From: Biomaven  Read Replies (1) | Respond to of 52153
 
a clear picture of how VEGF production sorts out among cancer types

I do know that VEGF is overexpressed in stomach cancer as well as colon cancer. Pancreatic cancer seems more variable.

When the dust settles, I'll bet they find a few dozen growth factors that are significantly overexpressed in various cancers. It's going to be quite a challenge to figure out what combinations of factors are critical for each different cancer type (and potentially stage).

Note incidentally that there is also quite a bit of work on anti-VEGF in macular degeneration as well as cancer. For example, Eyetech recently announced a very significant partnership with Pfizer in this area. (Incidentally their drug, Macugen, was licensed from GILD). Also I think RNAI has a similar program.

Peter



To: scaram(o)uche who wrote (8431)5/20/2003 2:58:20 PM
From: Elmer  Respond to of 52153
 
thanks again.