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Politics : Foreign Affairs Discussion Group -- Ignore unavailable to you. Want to Upgrade?


To: LindyBill who wrote (99337)5/28/2003 5:39:02 PM
From: Noel de Leon  Respond to of 281500
 
A Google search using roundup weeds brought this article.

ghorganics.com

Pesticide and Environmental Update

Is Roundup Killing More Than the Weeds?



an article from The Sun (Malaysia),

Concerns Over Glyphosate Use
Monsanto and PAN are embroiled in a hot debate over safety of a widely-used
herbicide. S.Puvaneswary has both sides of the story.
A widely-used herbicide which accounts for 48% of the Malaysian market in
pesticides may not be safe to use. A recent study which shows clear links
between exposure to the herbicide glyphosate and non-Hodgkin's lymphoma
(NHL), a form of cancer that afflicts the lymphatic system, has caused
worldwide concern over the safety of the herbicide on humans. The study was
conducted by eminent oncologists Dr Lennart Hardell and Dr Mikael Eriksson of Sweden and published in the journal Cancer by the American Cancer Society on March 15.

It maintains that exposure to glyphosate "yielded increased risks for NHL".
"What these scientists unearthed is indicative of the long-term chronic
effects of pesticides", said Sarojeni V. Rengam, executive director,
Pesticide Action Network (PAN) Asia and the Pacific. "In this case, where
there are serious implications to human health, the precautionary principle
must apply," she said.

"We have to take precautions against using these dangerous chemicals." The
widely-used herbicide glyphosate indiscriminately kills off a wide variety of
weeds after application and is primarily used to control annual and perennial
plants.

PAN has called on the government to look at its regulatory standards on
glyphosate residues because if such monitoring is not immediately done, the
health of Malaysians would be at risk as glyphosate accounts for about 48% of
the Malaysian market in pesticides, according to AGROW Crop Protection
Report, 1996.

The Hardell study is the centre of a debate between Monsanto, which refutes
its findings, and PAN which upholds the study. The US firm manufactures
Roundup, a glyphosate herbicide.

The arguments and counter-arguments of both parties relating to the study
were sent to the SUN.

Monsanto's Argument:
Previous evaluations conducted by the US Environmental Protection Agency
(EPA) and the World Health Organization (WHO) suggest that glyphosate is not mutagenic or carcinogenic. WHO and the Food and Agriculture Organization (FAO) have approved the safety of glyphosate residues in
genetically-engineered Roundup Ready soya beans.

PAN's Counter Argument:
The EPA and WHO evaluations were done more than five years ago and are based mainly on data submitted to them by Monsanto. These evaluations did conclude that "there is no evidence of mutagenicity or carcinogenicity" based on the available data, but they do not support definitive assertions that glyphosate "is not mutagenic or carcinogenic". (Nor did they look at the entire poison formula, contaminants and/or synergistic effects.)

Previous EPA and WHO evaluations which made similar claims for other
chemicals had to be revised as new evidence came to light. The establishment of the WHO's Acceptable Daily Intake (ADI) is based on limited studies using limited parameters which do not account for vulnerable groups such as children, the elderly, the sick and other groups that might have increased susceptibility to glyphosate exposure.

Monsanto's Argument:
Well-characterised scientific literature reviewing over 1,000 studies over
the last 25 years demonstrates that extraordinary safety of glyphosate, the
active ingredient of Roundup herbicide. (it is against the Federal Law to say
even the labeled use of any economic poison is "safe" - obviously this does
not apply to the poison producers.)

PAN's Counter Argument:
There are very few independent studies on glyphosate available in published
scientific literature and no responsible reviewer of health science
literature, health scientist, or toxicologist would claim "extraordinary
safety" for glyphosate. Data from independent sources indicate serious
concerns about glyphosate toxicity. In 1995, the National Poisons Centre
reported an increase of glyphosate poisonings in Malaysia. In the UK, it was
reported that glyphosate was the most frequent cause of complaints and
incidents from pesticides recorded by the Health and Safety Executive.

Monsanto's Argument:
The epidemiology study conducted by oncologists Hardell and Eriksson did not find statistically significant associations between NHL and reported cases of fungicides and herbicides. Reported use of glyphosate, along with reported
use of several other herbicides showed a weak, not statistically significant
association with NHL.

PAN's Counter Argument:
A weak association is an association nevertheless, and could be statistically
significant given that 211 million kg of glyphosate were used last year and
the volume is growing at an average of 20% per year. The Hardell study
observed a positive association between exposure to glyphosate and NHL, in
which, chance and bias could be ruled out with reasonable confidence.

Monsanto's Argument:
Exposure to glyphosate is not likely to be meaningful. Exposure opportunity
is almost exclusively through dermal contact. Glyphosate has shown very low
skin penetrability in experimental studies.

PAN's Counter Argument:
Scientific principles, particularly toxicokinetics, must apply. The exposed
person will be subjected to risks of adverse effects, known or unknown. Even
if the chemical has low vapor pressure, appreciable inhalation exposure can
occur since micro-droplets can form and particulates can be carried by
movement of air. Oral intake can also occur through contaminated food or
water. The fact that glyphosate is a systemic herbicide and persists in the
environment for a relatively long period of time (as long as 3 years in soil)
makes it likely to enter the body through residues (contamination) in food
and water. Residues are unlikely to be removed from plant tissues and use of glyphosate in animal feed can result in residues in animal food products such as meat, milk and eggs. Residues are stable to up to one year in plant materials and water and up to two years in animal products in storage.

Finally PAN upholds the right of farmers, workers and consumers to be
informed, and to have access to all the information on poisons that they are
using, spraying, and possibly consuming.

In its statement to the SUN, PAN upholds the right of people to make informed
choices on what they may be exposed to, and whether they are willing to beexposed to these chemicals.

PAN Asia Pacific
P.O. Box 1170
10850 Penang
Malaysia
Tel.: 604-6570271
604-6560381
Fax.: 604-6577445



To: LindyBill who wrote (99337)5/28/2003 5:43:47 PM
From: Noel de Leon  Respond to of 281500
 
And another article.
biotech-info.net

Here the word pesticide is used instead of herbicide in the last but forth paragraph. Hope this "lapse" does not invalidate your enjoyment of the article.

"Roundup-resistant weeds are cropping up"
The herbicide is so popular that it may not be as effective as it was initially

Philip Brasher
Des Moines Register
Washington Bureau
January 10, 2003

Washington, D.C. - Few inventions have altered agriculture recently as much as Roundup weedkiller, but now scientists are concerned that farmers are using the herbicide so heavily it is losing its effectiveness against some of the world's peskiest weeds.

"It's going to happen. It's inevitable," said Bob Hartzler, a weed scientist at Iowa State University.

Known generically as glyphosate, Roundup is powerful yet environmentally benign. It has led to the widespread adoption of soil-saving techniques that reduce land erosion and combat global warming. Even home gardeners are likely to have a version of Roundup in their garage arsenal.

Roundup has been around for nearly 30 years but exploded in popularity in the late 1990s with the development of genetically engineered soybeans, cotton and other crops that are immune to the herbicide. That change means farmers can spray their fields with the relatively cheap weedkiller whenever it's needed with no fear it will harm the crops.

Roundup-immune soybeans now account for 75 percent of all the soybeans planted nationwide and in Iowa. Some 33 million pounds of glyphosate were sprayed on soybean crops alone in 2001, a five-fold increase from 1995, according to the U.S. Department of Agriculture.

Scientists are finding Roundup-resistant weeds in a variety of states, from Iowa to Delaware. Scientists are so concerned that some 200 showed up for a symposium on the issue last month in St. Louis.

Monsanto Co., which invented both Roundup and the Roundup-immune crops, has applied to the Environmental Protection Agency to alter Roundup labels to add special instructions for farmers in areas with resistant weeds.

A rival manufacturer of glyphosate, Syngenta, is advising farmers not to apply the chemical more than twice in every two-year period and not to plant glyphosate-resistant crops in the same field every year.

"The warning signs are already out there," said economist Charles Benbrook, a critic of the biotech industry and a former executive director of the National Academy of Sciences" board on agriculture.

If herbicide-tolerant weeds gain hold, land prices could slip and farmers would be forced to start using additional chemicals, adding to their costs and potentially increasing environmental risks.

No alternatives to Roundup are on the horizon. Industry experts say Roundup has been so effective for so long that there has been no financial incentive for chemical companies to develop a substitute.

Farmers love the bioengineered soybeans because they say Roundup makes it easier and cheaper to control the weeds. Ron Heck of Perry, Ia., says he used to spend $20 to $40 an acre on weed control. Now the cost is down to about $15 an acre, even accounting for the special fee for the seed.

Growers also say the biotech soybeans have allowed them to farm more land and spend more time with their families, or in some cases take a second job.

Monsanto throws in some more incentives: If the biotech crops fail, the company will refund some of the seed cost. And if the herbicide doesn't kill the weeds, farmers can get additional Roundup for free.

Roundup is so effective as a herbicide that many farmers are no longer tilling their fields to control weeds. Less tillage means less erosion and stores carbon in the soil, thereby limiting the production of the greenhouse gases blamed for global warming. No-till soybean acreage increased by 35 percent from 1995 to 2000, according to one study.

Herbicide resistance in weeds is nothing new. It happens regularly with weedkillers, except, until recently, with Roundup.

Some of the first significant reports of Roundup-resistant weeds in the United States surfaced in Delaware. Mare's-tail, or horseweed, that could not be killed by the herbicide was found on several farms in 2000. Scientists said they had to spray the weeds with 10 times the recommended rate of the herbicide to kill the plants.

Scientists in Iowa and Missouri have found fields with types of waterhemp, a prolific Midwestern weed, that are significantly more tolerant of glyphosate than others. More than a quarter of the weeds collected from one Iowa field survived being treated with Roundup.

The scientists say it remains to be seen how quickly the hardier weeds will spread.

"Everybody is in reasonable agreement that the evolution of glyphosate resistance in waterhemp is inevitable," said ISU scientist Mike Owen.

Monsanto, which generates 50 percent of its annual sales from Roundup, says there are two U.S. weeds that are resistant to it - mare's-tail and ryegrass - but company officials say the problem isn't serious. They don't consider waterhemp resistant.

David Heering, who manages the technical side of the Roundup business for Monsanto, said rival companies like Syngenta are trying to discourage farmers from using the glyphosate-resistant, or Roundup Ready, crops because they cut into sales of other herbicides. "As we see increased adoption of Roundup Ready, they are going see lost business," Heering said.

Chemical companies have another reason to discourage use of Roundup Ready crops: Monsanto profits from the special technology fee it charges on every bag of the gene-altered seed. Other companies do not.

Syngenta officials say they are trying to ensure that glyphosate, which they market as Touchdown, remains effective.

In Iowa, farmers typically don't plant soybeans in the same field two years in a row, as some Eastern growers do, so there is less chance of overusing the herbicide. But some farmers are considering growing Roundup Ready corn in addition to Roundup Ready soybeans, and that could increase use of the weedkiller and speed up the spread of resistant weeds, some scientists say.

More about Roundup

Roundup herbicide, introduced by Monsanto Co. in 1974, works by interfering with a key enzyme in plants and preventing then from making essential amino acids. People and animals don't have the enzyme, making the chemical relatively safer than many other pesticides.

POPULARITY: Use of Roundup, known generically as glyphosate, exploded when Monsanto scientists figured out how to make crops immune to it by inserting into them a soil bacterium gene. The bacterium contains an enzyme similar to the one that plants naturally have. The biotech crops accounted for about 75 percent of the soybeans, 50 percent of the cotton and 10 percent of the corn planted by U.S. farmers last year.

FRIENDLY: Roundup also is widely used by homeowners and along roads and railways. Glyphosate is considered so environmentally friendly that it is used to control weeds on the ecologically unique Galapagos Islands.

AWARDS: The Monsanto scientist who first identified the herbicidal activity in glyphosate was awarded the National Medal of Technology in 1987. In 1994, Farm Chemicals magazine called Roundup one of the top 10 products that "changed the face of agriculture."

** NOTICE: In accordance with Title 17 U.S.C. Section 107, this material is distributed for research and educational purposes only. **