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Biotech / Medical : biotech binary events -- Ignore unavailable to you. Want to Upgrade?


To: nigel bates who wrote (50)6/5/2003 11:18:49 AM
From: Biomaven  Read Replies (1) | Respond to of 295
 
historic survival rates for metastatic disease prior to the availability of immunotherapy ?

The trouble is you need more than median survival and 5-year survival, which is all that is usually quoted.

The paper I quoted actually has the right curves - it's just that this current trial is starting mid-way along their curves, after people have already failed, and I don't know how far along to start. Also now that I think about it some more, I presumably need to exclude their long-term survivors altogether, because I assume they didn't ever show progression. So maybe the long tails in my article are deceiving.

On another issue altogether, anyone have any idea of what the IP protection here is? Further, are they offering anything more than the same shark gloop you can buy at health food stores?

See, for example:

realife.com

Peter
P.S. Don't know if we should take this discussion to another thread or not. I assume this one is low-profile enough so that we aren't actually bothering anyone here.



To: nigel bates who wrote (50)6/5/2003 8:38:48 PM
From: Miljenko Zuanic  Read Replies (2) | Respond to of 295
 
One article (if you need copy let me know) and two link of interest.

Note that clear cells carcinoma respond better to immunotherapy than other forms of the kidney cancer. Also, no therapy can do much (anything?) about primary tumor, so far. Further, stable disease so far did not translate into survival benefit in RCC randomized trials.

Journal of Clinical Oncology, Vol 20, No 1 (January 1), 2002: pp 289-296
biologictherapy.org
moffitt.usf.edu