To: Johnny Canuck who wrote (39752 ) 6/18/2003 3:39:55 AM From: Johnny Canuck Read Replies (1) | Respond to of 71524 Pfizer Cuts 2003 Earnings Outlook Tuesday June 17, 6:15 pm ET By Jed Seltzer and Ransdell Pierson NEW YORK (Reuters) - Pfizer Inc. (NYSE:PFE - News) said on Tuesday inventory build-ups at drug wholesalers would cut into its 2003 earnings, but its 2004 earnings will rise by about 23 percent, boosted by cost cuts from an acquisition and increased sales of key medicines. Pfizer said wholesalers had built up excessive supplies of Pharmacia drugs, which will hurt sales of the same products in coming months, thereby trimming full-year earnings by 7 cents. The company now expects 2003 per-share earnings of $1.73, about three cents below the average Wall Street estimate. Customers typically keep fairly large supplies of the kinds of drugs Pharmacia sold, including ones for cancer and glaucoma, a former Pharmacia official said on Tuesday. For 2004, the company estimated earnings of $2.13 per share, above the average estimate of $2.06 per share. Shares of Pfizer, the world's largest drugmaker, jumped nearly 5 percent on the outlook, which was released as it gave fresh details on its pipeline of experimental drugs at an investor conference in New York. It later closed on the New York Stock Exchange (News - Websites), where it was the most active issue, at $36.18, near a 52-week high of $37.04 Revenue is expected to total $54 billion in 2004 from a combined Pfizer and Pharmacia, compared with about $45 billion last year. That represents 10 percent growth per year. OUTLOOK FOR GROWTH "This is what Pfizer needed to do -- convince people they can continue to grow," said analyst Barbara Ryan of Deutsche Bank. Despite the robust outlook, investors and analysts remained concerned that Pfizer is too dependent on big acquisitions -- Pharmacia Corp. in April and Warner Lambert Co. in 2000 -- to boost profit. They want to see the fruits of a research budget that exceeded $5 billion last year. The company is slated to lose U.S. patent protection in the next three years on five of its top-selling medicines that had combined sales of $11.5 billion last year -- or about one fourth of Pfizer and Pharmacia's total revenue. The question is whether Pfizer's existing and future drugs can compensate for the huge drop-off in sales when those five face generic competition. "I think Pfizer will be OK until 2005, but you have to worry about 2006 and beyond," said Richard Schneider, an analyst at DuPont Capital Management. He added he was optimistic Pfizer will come up with enough big new drugs to make up for shrinkage in older drugs once they face generic competition. Among the most anticipated new treatments are two combination pills that would include Pfizer's cholesterol drug Lipitor, the world's top-selling medicine with more than $8 billion in annual sales. One combo drug would raise HDL, or "good" cholesterol, levels by 50 percent. Most cholesterol drugs lower LDL, or "bad" cholesterol, but raise HDL just a bit. A drug that significantly affects both levels in one pill could become widely prescribed by physicians, analysts said. Pfizer also expects to start marketing a drug next year that combines Lipitor with Norvasc, its top-selling blood pressure drug. Millions of Americans have both hypertension and high cholesterol. "Lipitor and Norvasc in one pill could serve a very big market," said Sena Lund, a research analyst for Cathay Financial. Lund said the combination could generate annual sales of $2 billion to $3 billion. Both combo medicines could also help prop up Lipitor, whose sales growth has slowed in recent quarters. Investors and analysts want Pfizer to prove it can boost earnings through new drugs rather than by squeezing significant savings from overlapping research and manufacturing. Pfizer research executives sought to address that concern at the conference, pointing to the Lipitor combinations as well as experimental drugs for asthma, smoking cessation, impaired vision, cancer, epilepsy, osteoporosis and chronic obstructive pulmonary disorder.