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Biotech / Medical : sciclone pharmaceuticals -- Ignore unavailable to you. Want to Upgrade?

To: Skywatcher who wrote (1106)	6/28/2003 9:17:01 PM
From: JEB	Respond to of 1137

The latest and greatest choices on the market are: Pegasys (made by Roche) which for some reason has slightly less side effects but seems to be just a remix version of Pegintron (interferon-A2b). Pegintron (made by Schering Plough) which has several side effects but most of those are temporary and range from inconvenience to treatable severe irritations. Both are married to cocktail therapy in conjuction with either Copegus (Roche's ribavirin pills) or Rebetol (Schering Plough's ribavirin pills). The ribavirin therapy has many more side effects which are undesirable (ask the SARS patients they'll tell you since the injectable form of ribavirin called rebetron was tested on them). Zadaxin is aiming (IMO) to eliminate the need for the ribavirin therapy as a replacement or at the very least to be added as a second adjuvant in the cocktail therapy.

To: Skywatcher who wrote (1106)	6/29/2003 2:46:43 AM
From: JEB	Read Replies (2) \| Respond to of 1137

Ignore my last post. I've been researching HCV lately, ...and, ...well, ...screwed than one up. I was referring to HCV therapies. Allow me to set the record straight here. For HBV therapy: Pegintron (Schering Plough) Interferon therapy has the side effects I mentioned earlier. Epivir HBV (GlaxoSmithKline) Lamivudine therapy has little side effects but can cause mutant HBV cells. Hepsera (Gilead) Adefovir Dipivoxil therapy is the newest on the market and has little side effects except for kidney problems which appear to be reversible. Zadaxin would be the first adjuvant (secondary drug - cocktail therapy) approved for HBV therapy in Japan. Also, any drug like Zadaxin that can take the "edge" off the chemotherapy drugs has got to help take the "edge" off of these drugs as well.