To: Miljenko Zuanic who wrote (259 ) 7/22/2003 6:39:07 PM From: Miljenko Zuanic Respond to of 590 Dam, who negotiate this deal with Lonza? Lonza can do excellent by this bios practice: license and than cancel! <<These start-up costs included the $28 million cancellation fee, which Abgenix will pay to Lonza in four equal quarterly installments, to eliminate Abgenix's commitment to pay approximately $46 million in total monthly fees through August 2006.>> Press Release Source: Abgenix Abgenix Announces Second Quarter 2003 Financial Results Tuesday July 22, 4:14 pm ET FREMONT, Calif.--(BUSINESS WIRE)--July 22, 2003--Abgenix, Inc. (NASDAQ:ABGX - News) today reported financial results for the second quarter ended June 30, 2003. For the quarter ended June 30, 2003, the company reported a net loss of $66.7 million or $0.76 per share, compared to a net loss of $79.7 million or $0.92 per share for the same period in 2002. The net loss for the second quarter of 2003 included a charge of $28 million resulting from Abgenix's negotiated cancellation of a November 2000 agreement with Lonza Biologics for the use of one of its manufacturing facilities, which Abgenix no longer needs. The net loss for the second quarter of 2002 included impairment charges of $37.5 million for unrealized losses on investments in common stock related to various collaborations. Contract revenues for the second quarter were $2.4 million, compared with $2.5 million for the same quarter in 2002. Including interest income, total revenues for the second quarter were $5.1 million, compared with $7.6 million for the same period in 2002. Contract revenues for the quarter primarily included license fees and milestone payments from customers and collaborators. Such revenues typically depend on the timing of certain events and vary from quarter to quarter. Expenses for the second quarter of 2003 were $71.8 million, compared with $87.3 million for the same quarter in 2002. Second quarter 2003 expenses included $41 million in costs of starting up the company's antibody production facilities. These start-up costs included the $28 million cancellation fee, which Abgenix will pay to Lonza in four equal quarterly installments, to eliminate Abgenix's commitment to pay approximately $46 million in total monthly fees through August 2006. Net cash used in operating activities in the second quarter of 2003 was $28.9 million. Abgenix ended the second quarter with approximately $307.4 million in cash, cash equivalents and marketable securities. In addition, Abgenix holds long-term investments, primarily equity in corporate collaborators, valued at $23.4 million. "During the second quarter, we advanced several key collaborations and continued to deliver on our strategy of being the partner of choice in discovering, developing and commercializing monoclonal antibodies," said Ray Withy, Ph.D., president and chief executive officer of Abgenix. "We are also extremely encouraged by the interim phase 2 data for ABX-EGF, and are working closely with Amgen to move the clinical development program forward as efficiently as possible." Recent company highlights include: Announcing a milestone payment resulting from the filing of an IND by Pfizer to begin clinical trials with a second antibody licensed from Abgenix as part of an ongoing research alliance with Pfizer to generate fully human antibodies for various diseases. Presenting interim phase 2 results of ABX-EGF in advanced colorectal cancer at the 39th annual meeting of the American Society of Clinical Oncology. Results from the multicenter study showed that 4 of 40 efficacy-evaluable patients with metastatic colorectal cancer experienced partial responses, and 22 of 40 had stable disease after 8 weeks. Advancing an ongoing collaboration with Human Genome Sciences, which has acquired a commercial license to develop and commercialize a XenoMouse®-generated antibody to a key HIV receptor, the chemokine receptor CCR5. Forming an alliance with Microscience, a biotechnology company based in the UK, to develop, discover and commercialize monoclonal antibodies against certain infectious diseases. Conference Call Information