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To: AuBug who wrote (189)8/10/2003 6:31:16 PM
From: scaram(o)uche  Respond to of 684
 
D2E7 from Abbott is phage-derived. Too early to say what the real world (marketed) experience is. But an antibody (human) -- minus carbohydrate -- is an antibody (humanized) is an antibody (phage).

When it's all done and in, immunogencity of MAbs will depend on other stuff.

One might say that -- minus mine -- there's rather substantial expertise in this area among SI contributors.

edit: sorry, Erik... didn't see your response.