To: suncasper  who wrote (352 ) 10/20/2003 8:11:35 PM From: thebeach     Read Replies (1)  | Respond to    of 356  Reuters                Procyon Biopharma jumps on U.S. anti-HIV patent                Monday October 20, 12:00 pm ET                 MONTREAL, Oct 20 (Reuters) - Shares in Procyon Biopharma Inc. (Toronto:PBP.TO - News)                jumped 19 percent after the Canadian biotech firm said it had been granted a U.S. patent                covering protease inhibitors for HIV/AIDS treatment.                                                         Protease inhibitors are an important                                                         part of the drug-treatment therapy                                                         commonly used for AIDS patients.                                                         Shares in the Montreal-based                                                         company rose 16 Canadian cents or                                                         19.05 percent to C$1.00 as more than                                                         two million shares changed hands on                                                         the Toronto Stock Exchange (News -                                                         Websites) .                                                         Procyon's stock value has doubled                                                         since the beginning of the year.                                                         The company said on Monday the                                                         U.S. patent covered compounds that                                                         have been shown to inhibit the activity                                                         of HIV aspartyl protease, an enzyme                essential for the virus's maturation and infectivity.                "The patent also includes the protease inhibitor PL-100, Procyon's drug candidate that has                demonstrated activity against HIV strains containing multiple mutations in the protease gene,"                Procyon said in a statement.                The company said research showed PL-100, a next-generation inhibitor, was active against                HIV/AIDS strains that were resistant to current protease inhibitors.                "As nearly three-quarters of HIV patients on drug therapy are experiencing drug or multi-drug                resistance, and about 20 percent of the newly diagnosed patients are now presenting with drug                resistance, new protease inhibitors are constantly needed," said Hans Mader, president and                chief executive officer of Procyon Biopharma.                Mader said PL-100 should benefit from an "extensive commercial life".