To: nigel bates who wrote (1502 ) 10/14/2003 2:58:59 PM From: tuck Respond to of 1784 >>BOTHELL, Wash., Oct. 14 /PRNewswire-FirstCall/ -- Epoch Biosciences, Inc. (Nasdaq: EBIO - News), a provider of proprietary products that accelerate genomic analysis, announced it has reached agreement with Millennium Pharmaceuticals, Inc. to supply Epoch's MGB Eclipse(TM) Probe Systems for multiplexed gene expression analysis. As part of the agreement, Epoch Biosciences will develop, functionally test, and supply multiplexed MGB Eclipse assays to gene targets specified by Millennium. These Assay Validated Probe Systems are designed to support Millennium's internal target validation systems and quality control processes while delivering higher performance overall. Assay Validated Probes are a unique product that Epoch has launched for key customers. The program offers custom MGB Eclipse probe assays for customer-defined targets with guaranteed assay performance following extensive functional testing by Epoch. William G. Gerber, M.D., chief executive officer of Epoch, said, "Our overriding product development goal has been to achieve levels of performance and reproducibility that satisfy the most demanding research organizations and support the most challenging projects. Our Assay Validated Probes program is an expression of our confidence in our MGB Eclipse Probe System and our ability to serve performance-driven customers. Millennium's rigorous evaluation process is another validation of the capabilities of MGB Eclipse in a real world research setting." MGB Eclipse Probe Systems MGB Eclipse Probe Systems are probe and primer sets used for a variety of genetic analysis applications, such as gene expression profiling, SNP analysis, and pathogen detection. The systems are compatible with the existing installed base of real-time PCR instruments and reagent systems that have been widely adopted around the world and are considered the gold standard in genetic sequence detection. MGB Eclipse Probe Systems incorporate Epoch's proprietary technologies, including MGB(TM), modified nucleotides, and specialized dye and quencher technologies, and are designed by sophisticated easy-to-use software to support custom ordering of unique probe and primer sequences specific to the needs of individual researchers. As a result, MGB Eclipse Probe Systems not only offer a competitive alternative for routine sequence analysis, they often outperform leading chemistries for more specialized applications such as splice variants and problematic SNPs.<< SNiP Cheers, Tuck