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Biotech / Medical : Biotech Short Candidates -- Ignore unavailable to you. Want to Upgrade?


To: tuck who wrote (592)10/20/2003 5:39:28 PM
From: Icebrg  Read Replies (1) | Respond to of 897
 
>>What do you think? It appears you've started to look at CTIC recently.>>

Yes, I have bought some recently. Mainly because of Pixantrone (Novus Pharma) and Trisenox. Not the best timing it seems. I listened to the CC and the company claimed they were almost pleased with the reduction as it would make it possible to pump more Xyotax into their patients (i.e. more cycles). The Data Safety Board had suggested a reduction from 235 mg/m2 to 210, but the company decided that 175 mg/m2 was more suitable as that was what they had used in the past. For flirting with a disaster they seemed pretty upbeat. They will do a corresponding reduction for PS2 status patients in the Stellar 2 trial. I am sure there was some spin there, but they didn't seem to be very concerned about the incident. It is interesting that they broke the news today and not tomorrow when they publish their results.

Erik



To: tuck who wrote (592)10/20/2003 6:32:56 PM
From: Miljenko Zuanic  Read Replies (2) | Respond to of 897
 
XYOTAX did not work WELL at 225 mg/m^2 and will work worse at 175 mg level. PG-formulation is too stable (low level of the free P at the cancer site) and majority of the drug (intact) is secreted in urine.

They can be pleased as much as they want, but investors will be disappointed at end. It is my opinion.

Miljenko