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To: elmatador who wrote (43531)12/17/2003 10:03:56 PM
From: Henry Niman  Read Replies (1) | Respond to of 74559
 
I read the NEJM article out today and covered by some media.

Earlier media reports suggested the Flight CA-112 flight (2 in report) had even more consequences than described in the paper, which indicated 22 on board developed SARS from the index case. The report listed 4 from Taiwan, but media reports indicated that there were 6 from Taiwan who developed SARS. The article indicated that 5 passengers subsequently died and they transmitted SARS to 13 others, two of whom died.

I suspect the numbers were considerably higher. The index case arrived in Beijing on March 15 and died on March 20. While in Beijing he was transferred to several hospitals, and HCW's trying to revive him contracted SARS. However, I suspect much more SARS was transmitted by the two flight attendants who were the index cases for Hohhot. I believe one of the husbands of the flight attendants died and several hundred in Hohhot developed SARS. At least one of the attendants developed symptoms, but was told to keep flying. I'm not sure how many of her flights were investigated.

However, the paper looked at two other flights. I believe that one was with the pre-symptomatic patient who I suspect was the source of TW1, which didn't have any mutations other than the standard Metropole Hotel mutations.

The other flight was the one returning the Taiwanese passengers. 4 (or 6) developed SARS, although no one on the flight did. However, media reports indicated that an 8 year old son of one of the infected passengers developed SARS in Taiwan.

Of interest from a political point of view was the two Chinese government officials. One flew back to Beijing from Bangkok. He subsequently died. I believe it was the other official who flew back to Beijing and sat next to Pekka Aro. Pekka Aro was a government official from Finland. He developed SARS in Beijing and died in route back to Hong Kong after his condition deteriorated at the hospital in Beijing. His death made it clear that there was a SARS problem in Beijing. At the time, the government was still denying that there was a problem in Beijing.

Media reports also indicated that a least one of the people serving high government officials developed SARS and this further heightened SARS awareness in government officials.

Thus, flight CA-112 probably led to significantly SARS cases in Beijing as well and Hohhot and brought SARS very up close and personal to high government officials.