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Biotech / Medical : Biotech Lock-Up Expiration Hell Portfolio -- Ignore unavailable to you. Want to Upgrade?


To: tuck who wrote (881)12/18/2003 11:02:56 AM
From: keokalani'nui  Respond to of 1005
 
I've been meaning to do the same and promise I will someday.



To: tuck who wrote (881)12/22/2003 3:19:06 PM
From: scaram(o)uche  Respond to of 1005
 
Genitope.... it's even more complex than just the "personalized" angle. We've discussed this before, somewhere.

Sigh, sure wish SI's search function was worth crap.

1. unlike most "cancer antigens", the idiotype of NHL is real. the target for this vaccine WILL allow for effective and specific anti-cancer responses.

2. however, the antigen is unfortunately defined by a genetic region which is known for it's astronomically high rate of somatic mutation.

So, you win some, you lose some.

Idec has tried the concept, with a little less spit and shine. Remissions were not durable. I mentioned that (and the LSBC project) to Genitope's CEO a two or three years ago at H&Q. He said that, if the patients do relapse with an antigen-negative cancer, their system is fast enough to just treat the patient's then-problematic idiotype.

Easy to say.

I haven't looked at the S-1. Please forgive any ignorance that may derive from not having looked at them in 2-3 years. This may all be old news.