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To: elmatador who wrote (43996)	12/29/2003 10:33:59 AM
From: RealMuLan	Read Replies (1) \| Respond to of 74559

Here are some good news for those who are fighting obesity<g> The end of obesity? Researchers find way to melt fat from muscle The Asahi Shimbun -------------------------------------------------------------------------------- Melt away fat without exercise? It's almost too good to be true. But researchers at the University of Tokyo may have found the way. If drugs can be developed to activate a receptor protein in muscle, whose function was previously unknown, it just might spell the end of obesity and even diabetes. The findings, by a research group at the Research Center for Advanced Science and Technology, were released Wednesday in the U.S. journal Proceedings of the National Academy of Sciences. Juro Sakai, professor of metabolic medicine at the center, researcher Toshiya Tanaka and others found that when peroxisome proliferator activated receptor Delta (PPAR Delta) is activated by a chemical, fat inside muscle cells can be burned without exercise. Other body fat is not lost in the procedure. By activating the PPAR Delta of a mouse that had been fed food high in fat, researchers were able to limit its increased body weight to about 60 percent that of an untreated mouse, though the amount of exercise and food intake remained the same for both. When it was injected with insulin, the treated mouse's blood sugar levels dipped. ``The effect of body weight reduction was weaker on non-obese mice and there were no side effects, so this system can be deemed safe,'' Sakai said.(IHT/Asahi: December 26,2003) (12/26) asahi.com