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Biotech / Medical : Abgenix, Inc. (ABGX) -- Ignore unavailable to you. Want to Upgrade?


To: Icebrg who wrote (312)2/3/2004 8:17:44 AM
From: nigel bates  Respond to of 590
 
what Abgenix think that they are doing...

No more than this ?

"...It also meets our goal to advance one non-oncology product candidate into the clinic this year..."



To: Icebrg who wrote (312)2/4/2004 5:32:29 PM
From: Icebrg  Read Replies (1) | Respond to of 590
 
>>It would really be interesting to hear what Abgenix think that they are doing.>>

Withy talked a little about this at the Merril Lynch presentation. The main potential advantages might be:

- The drug "will" have a direct dose-dependent impact on the PTH-levels. The mAb binds directly to PTH, while alternative drugs (like for example NPSP/Amgen's Cinacalcet) works indirectly.

- Abgenix expects their drug to have a long(er) half-life making it possible to tailor administration of the drug to the dialyses these patients are receiving.

Erik