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Biotech / Medical : Cell Therapeutics (CTIC) -- Ignore unavailable to you. Want to Upgrade?


To: caly who wrote (223)6/10/2004 1:03:08 PM
From: tuck  Read Replies (1) | Respond to of 946
 
>>GENEVA, June 10 /PRNewswire-FirstCall/ -- Arsenic trioxide will be featured in seven presentations at the 9th Congress of the European Hematology Association (EHA). Cell Therapeutics, Inc. (CTI) (Nasdaq: CTIC; Nuovo Mercato: CTIC) markets TRISENOX® (arsenic trioxide) injection.

For a list of presentations at ASH, refer to the table below. To access a complete list of abstracts, refer to the conference website at ehaweb.org .

Trisenox(R) (arsenic Trioxide) Presentations

Date Time ABSTRACT Title
#

Fri., June 11 5:00 p.m. 118 The influence of arsenic trioxide
on the clonogenic capacity of
bone marrow in patients with
newly diagnosed chronic phase
chronic myelogenous leukemia
(CML)

Fri., June 11 5:00 p.m. 093 Treatment of new cases of acute
promyelocytic leukemia (APL) by
arsenic trioxide

Fri., June 11 5:00 p.m. 085 Treatment of newly diagnosed
patients with APL using
intravenous arsenic trioxide

Sat., June 12 5:15 p.m. 365 A phase I/II multicenter, safety
and efficacy study of combination
treatment with melphalan, arsenic
and vitamin C (ascorbic acid)
(MAC) in patients with relapsed
or refractory multiple myeloma

Sat., June 12 5:15 p.m. 522 Safety experience with TRISENOX
(arsenic trioxide) injection

Sat., June 12 5:15 p.m. 467 TRISENOX (arsenic trioxide) in
patients with myelodysplastic
syndromes (MDS): Preliminary
results of a phase I/II study

Sun., June 13 9:00 a.m. 801 Glutathione peroxidase activity
and glutathione level in patients
with relapsed multiple myeloma
treated with arsenic trioxide


About TRISENOX®

TRISENOX® (arsenic trioxide) is marketed by Cell Therapeutics, Inc. (CTI). TRISENOX® was approved for marketing in 2000 by the U.S. Food and Drug Administration to treat patients with relapsed or refractory Acute Promyelocytic Leukemia (APL), a rare, life-threatening form of cancer of the blood. TRISENOX® was granted marketing authorization from the European Commission in March 2002. APL, one of eight subtypes of acute myeloid leukemia (AML), represents 10-15 percent of the more than 20,000 patients diagnosed with AML each year. TRISENOX® is currently being studied in more than 40 clinical trials in a variety of cancers.

U.S. marketing approval for TRISENOX® was granted based on results from a U.S. multicenter study in which 40 relapsed APL patients were treated with TRISENOX® 0.15 mg/kg until bone marrow remission or a maximum of 60 days. Thirty-four patients (85 percent) achieved CR. When the results for these 40 patients were combined with those for the 12 patients in a pilot trial, an overall response rate of 87 percent was observed.<<

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Cheers, Tuck