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Biotech / Medical : Guilford (GLFD) - Steadily Rising -- Ignore unavailable to you. Want to Upgrade?

To: tuck who wrote (477)	6/17/2004 4:15:56 PM
From: dalroi	Read Replies (1) \| Respond to of 496

Tuck big problem with aquavan is the propofol competition the original product now has generic versions which are very cheap (so hospital administrations like them very much) they now even sell the stuff in premade syringes which on screws on a pump and hop our anesthesist can go phoning :-) concerning the burning sensation in the first minutes - it takes only a very short while then one is asleep - one can prime with a dose off xylocaine iv - i had a propofol anesthesia and didnt remember the pain so i think aquavan isnt going to have a big pricing power cheers Stefaan

To: tuck who wrote (477)	6/18/2004 2:12:23 PM
From: rkrw	Read Replies (1) \| Respond to of 496

Like Harry, I had knee arthrsocopy surgery last fall. I requested propofol. Fell asleep rapidly, awoke rapidly, full consciousness before the cart rolled out of the operating room. Best was I awoke refreshed, no hangover effect. If they invented a sleeping pill that worked as well it would be a $10B drug :-) Lack of hangover effect is a prime reason nurses love administering propofol. Speeds up post procedure recovery and exit! Not sure exactly how this compares to propofol, probably similar? : <<<Brief episodes of apnea, defined as lack of spontaneous breathing for more than 15 seconds, were reported in 5% of patients and were successfully resolved without medical intervention. No patients required respiratory support or endotracheal intubation. There was no pain at the injection site reported. There were three episodes of mild, transient hypotension, all of which were successfully treated with a short course of fluids or ephedrine.>>> Lack of respiratory depression was one of aquavan's supposed benefits vs propofol. Are sleep apnea and hypotension linked to respiratory depression? I think glfd's commercial strategy is to go into markets where propofol can't be used. Head to head, aquavan is unlikely to do well against generic propofol. So a sound strategy imo. All that said, market cap is so low, if aquavan just gets approved, glfd stock will probably do well. Side note, interesting glfd transaction today. First thought, any ownership conflicts of interest?