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Gold/Mining/Energy : Nuvo Research Inc -- Ignore unavailable to you. Want to Upgrade?

To: gg cox who wrote (13672)	10/3/2004 12:04:34 PM
From: gg cox	Respond to of 14101

The one and ONLY reason I supported this stock all the way to the basement was this.. Message 18401823 Good article, thanks. I was able to acquire a 30 ml bottle of Pennsaid to Canada, via Barbados and Scotland<<<GGGGG>>>>for a test on the benefits of using Pennsaid for Osteoarthritis.This test had two purposes (1) to help my friend and (2) to satisfy my curiosity on how effective the product was.This experiment was not "blind" on my friends part as I gave him all the documentation regarding applying it and side effects etc.I asked him to write me out a few lines on what he thought of the product...the following is what I received today.(He his in his early sixties.) Quote. ""A friend asked me to try a new product Pennsaid for pain relief in my knees.The cartilage in my one knee has deteriorated through injury plus physical activities involving impact (jogging). I still like to maintain certain physical activities such as skating (hockey).I skate twice a week and before each activity I have been taking Aspirin and or Tylenol for joint pain relief.For the last three weeks I have substituted Pennsaid for the Aspirin/Tylenol.I applied it to my knees approximately one hour before the activity.I found the results to be very satisfactory.The pain relief equaled that of the Aspirin/Tylenol and I did not encounter any side effects. I would certainly recommend Pennsaid for joint Pain relief. IK""

To: gg cox who wrote (13672)	10/4/2004 10:40:43 AM
From: Chip	Respond to of 14101

Although the reason Vioxx caused heart problems is not certain, researchers believe its selective action on the COX-2 enzyme, but not the COX-1, throws the prostanoids involved in clotting out of balance. The result is a tendency for blood to clot -- and clots are the first step of heart attacks and most strokes. If that theory is correct, it means that Vioxx's cleverness was also its Achilles' heel. How would Vioxx be any different then Celebrex. Since they're both COX-2 drugs, is it possible Celebrex might also be pulled off the market sometime in the future?

To: gg cox who wrote (13672)	10/4/2004 11:39:56 AM
From: VAUGHN	Read Replies (1) \| Respond to of 14101

Dear gg The following reader's reply responded to a Canadian Press story in The Star: Though I don't live in Toronto I like to read The Star but now I wonder about the reliability of your news sources. In your article "Dimethaid stock soars 74 per cent in one day" you offer an analyst's opinion. " analyst Duncan Stewart of Tera Capital said ... "What's going on with Dimethaid is out and out ludicrous," said Stewart, pointing out that Pennsaid has yet to be approved by the U.S. Food and Drug Administration. "Does it actually work and have any effect?" Ludicrous or not, how can your analyst source be so ill-informed as to ask if Pennsaid actually works? When your source publicly reveals his ignorance that Pennsaid has had two Phase III studies (one published in the Canadian Medical Association Journal cmaj.ca ) and also completed a Phase IV study, all of which showed Pennsaid to be safe and effective --and that Pennsaid is approved in many countries-- I wonder if other published opinions can be believed. Why, before offering his opinion, didn't he inform himself not only of the foregoing but also about the study comparing Pennsaid with an oral NSAID (announced over a year ago and published in the J. of Rheumatology jrheum.com ) which showed equivalent effectiveness in reducing pain and increasing mobility, while having no adverse Gastro-Intestinal effects? Come to think of it, wouldn't it make sense for The Star to verify facts? Oh yes, your article also noted that "analyst Duncan Stewart of Tera Capital said most arthritis sufferers will likely switch from Merck's drug to Pfizer's Celebrex, another anti-inflammatory drug taken orally. " Perhaps. However at www.legal-database.com/celebrex.htm we see that “Concerns have been raised with regard to celebrex's impact on cardiovascular health, including an increased risk for stroke or heart attack, and even sudden death.... A study from the Cleveland Clinic appearing in the Journal of the American Medical Association revealed that the annual rates of heart attack Celebrex studies were increased. In those studies, .52% of patients taking an inactive placebo pill had a heart attack each year. The annual rate of heart attack was .80% for those taking celecoxib.” (I haven't verified the latter claim.) Frankly I think you should provide some information from Dimethaid to correct the mistaken views of your analyst. You might start with Jodi Peake, Director, Investor Relations, Tel: (905) 415-1446 ext. 257 Dimethaid Research Inc. 1405 Denison Street Markham, Ontario Canada L3R 5V2 Fax: 905-415-1440 E-mail: info@dimethaid.com Regards David Mitchell *** Also, the following from this morning's Cannacord Morning Coffee news letter: Dimethaid Research(DMX: TSX : $0.80), Net Change:0.34, % Change:73.91%, Volume: 11,522,900 Lamenting the loss of your Vioxx? Who needs Vioxx when you can have the (even more then we thought now)less-evasive Pensaid by Dimathaid? On Friday, the Journal of Rheumatology published a fantastic clinical study that demonstrates that the anti-arthritic lotion Pennsaid is safer than pills containing the same active ingredient. Plus, it works just as well as the maximum daily dose of comparable oral medication at relieving knee osteoarthritis symptoms. With US$2.5 billion worth of annual Vioxx sales up in the air, Diamathaid is bound to see some of it. At least in theory. The problem has always been that Diamathaid has been next to totally inept at selling their wonderful product. Yes, granted, how wonderful can it be if it doesn’t sell, you ask? Well, the doctors we have spoken to love the stuff. If you or any of your loved ones used Vioxx, tell them to ask their doctor about Diamathaid’s Pennsaid. Chances are, they will be thrilled. I suppose any press is good press. Vaughn