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Politics : Politics for Pros- moderated -- Ignore unavailable to you. Want to Upgrade?

To: abstract who wrote (75899)	10/9/2004 10:30:53 AM
From: Alastair McIntosh	Read Replies (1) \| Respond to of 793822

I agree that there may be a small benefit to the use of statins to someone who has already had a heart attack. However saying that statins reduce the incidence of heart attack 40% is wrong and misleading. For example consider the CARE trial which indicate the odds of escaping death from a heart attack in five years for a patient with manifest heart disease was 94.3% which improved to 95.4% with statin treatment. Not a great improvement. This tiny 1.1% improvement is never mentioned. Instead we read that the study indicates a 24% reduction in mortality because of a mortality of 5.7% in the control group compared to 4.6% in the treatment group. For healthy people the effect is even smaller. The WOSCOPS trial is touted as lowering mortality by 25% when the death rate for statin users declined from 98.8% to 98.4%.