To: kumar who wrote (76465 ) 10/11/2004 9:00:05 AM From: John Carragher Respond to of 793789 "The Stem Cell Debate" "The stem cell debate in N. America and Europe is shrouded in confusion, = media hype, political spin and biased, ill-informed input from = self-interested 'celebrities.' The debate centers around embryonic stem = cells which are promoted as a potential panacea. No mention is ever made = of any other sources of stem cells in these debates and the Earth = shattering moral, religious, ethical and legal objections to embryonic = stem cells are brushed aside as irrelevant to the overall 'good' which = will come from embryonic stem cell therapies. The subject has even = become a part of the US Presidential debate! In the early 1980's Bob Edwards and myself at Cambridge University = carried out the early experiments on embryonic stem cells using a mouse = model. We showed that the cells had enormous potential in that they = repaired radiation damage in mice very readily. Despite these promising = results in the laboratory we knew that to try to apply such technology = to the human in the clinic would raise serious objections. The current = debate highlights these early fears. One major, debate crushing point = which is consistently ignored is the fact that there is another easily = accessible, just as promising, source of stem cells. This source is = umbilical cord blood. Umbilical cord blood stem cells have been collected and transplanted = since 1988. Over 3,000 transplants have been carrier out Worldwide for = over 45 different diseases. These diseases include the leukemia's, = related blood disorders and repair of the bone marrow following high = dose chemotherapy for cancer. Umbilical cord blood can be collected at = the birth of every baby but currently less than 1% of deliveries = actually collect the cord blood. This life saving source of stem cells = is being discarded as biological waste on a daily basis at the same time = as other people argue for the creation of embryonic stem cells. = Umbilical cord blood stem cells have also been shown to be capable of = forming every tissue type in the body which is exactly the argument for = the use of embryonic stem cells. Umbilical cord blood stem cells carry = just as much, if not more, promise as embryonic stem cells in terms of = future therapies for a whole range of disease. The collection of umbilical cord blood stem cells is a quick, painless = and risk free procedure carried out just after a baby is born. A needle, = attached to a blood collection bag, is inserted into the umbilical cord = and blood is allowed to drain into the collection bag. This is then sent = to the laboratory for processing and freezing in liquid nitrogen. Once = frozen the sample is stable indefinitely. This process is a cheap and = easy way of obtaining stem cells which have all the potential of = embryonic stem cells without the objections. The stem cell debate is confused. The public is confused. The = politicians are confused. The hard fact is that we should be = concentrating all of our time, money and expertise on the development of = umbilical cord blood stem cell technologies. This is where the current = and future applications of stem cells truly lie." Dr. Peter Hollands, director of Cells for Life