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Gold/Mining/Energy : Vasogen-- VAS on TSE -- Ignore unavailable to you. Want to Upgrade?


To: caly who wrote (278)1/5/2005 7:17:50 PM
From: caly  Read Replies (1) | Respond to of 377
 
See bold for competing products...

Reducing inflammation as an emerging target for cardiovascular disease

A number of studies have shown that inflammation of blood vessels is one of the major factors that increases the incidence of heart diseases, including atherosclerosis (clogging of the arteries), stroke and myocardial infarction or heart attack. Studies have associated obesity and other components of metabolic syndrome, cardiovascular risk factors, with low-grade inflammation. Furthermore, some findings suggest that drugs commonly prescribed to lower cholesterol also reduce this inflammation, suggesting an additional beneficial effect of the statins.

This report focuses on various aspects of blood vessel inflammation; from definition to its causes. Further, the report analyses how inflammation could be a threat to the heart and life and various therapies to for reducing inflammation including losing weight, exercising and use of statins and ACE inhibitors. The report, step-by-step, covers information key to the emmerging field of vascular inflammation and concludes with a detailed evaluation of recent and future developments in this field and of leading companies advances agents that target inflammatory components of atherosclerosis. In particular preclinical and clinical data for Atherogenics' AGI-1067; GSK's Lp-PLA2 inhibitor; DeCode's DG031; Vertex's VX702; Vasogen's Celacade; and Incyte's INC3284 are all critically discussed.