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To: patron_anejo_por_favor who wrote (25218)1/24/2005 7:24:23 PM
From: Henry Niman  Respond to of 110194
 
Tamiflu is in the hopes and dreams category. Its expensive, has to be taken continuously, in short supply, and doesn't work well on N1, including H5N1. Roche is building a new plant in the US and other countries are talking about making generics, but the only reason its being considered is there isn't anything else (virus is resistant to Rimantadine and Amantadine).

Tami flu was used to try to rescue the tigers in the Thai Zoo, but they all died (147 out of 441 but the survivors were probably never exposed).

Best hope is a vaccine, but that was delayed because it was declared a select agent because the gene was modified to make the virus less lethal. I'm not sure how long it took to get ruling reversed, but trials have been delayed and won;t start for 406 weeks for Aventis (Chiron built a new facility, so they are behind Aventis)



To: patron_anejo_por_favor who wrote (25218)6/19/2005 12:02:01 PM
From: Henry Niman  Respond to of 110194
 
Amantadine resistance story in Washington Post is nonsense. Most H5N1 in China and everywhere but Vietnam and Thailand is Amantadine sensitive

news.google.com