To: Venditâ„¢ who wrote (4566 ) 2/3/2005 9:37:51 AM From: Walkingshadow Respond to of 8752 ALNY yesterday was boosted by an upgrade. ============================================== Alnylam Pharmaceuticals upgraded to Buy at BofA; tgt $9.50 (ALNY) 7.00 : Banc of America upgrades ALNY to Buy from Neutral with a $9.50 tgt. Firm believes the co is a leader in the rapidly-developing field of RNAi-based therapies, and that RNAi could be the next great therapeutic platform, transforming the pharmaceutical industry. They believe 2005 will be a catalyst-rich year, with multiple new programs announced and business development goals accomplished. ============================================== They have a strategic alliance now with MRK, which should provide them with the muscle needed for clinical trials and marketing. We'll see increasing news on this one over the next year or two, they are ahead of the pack in RNA interference. They have plans to conduct clinical trials related to respiratory syncitial virus and spinal cord injury, but there are many, many possible clinical applications of the technology. As I posted before, I don't often buy a good story. That said, I think you could make a good case for a long-term position, and a better case for repetitive trading. I think this one will eventually attract the mo-mo crowd, and the stock is driven by news (we'll see plenty of that this year). The float is 11 million shares with 45% held by insiders, and currently the stock is trading at $7.35. That means the remaining 6 million shares would require less than $40 million. Since the average daily volume is less than 200,000, the stock could be easily moved with just a few hundred thousand shares. The technology is exotic and not well understood by the street. The only thing missing from the mo-mo equation are shorts---less than 2% of the float is held short. And, right now the stock is extremely oversold and coming off support, with buy signals in place:139.142.147.218 T